Epigenetics
Scientists map proteins that let carcinomas change identity
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Researchers at Cold Spring Harbor Laboratory have identified key proteins and protein complexes that help certain carcinomas shift their cellular identity and potentially evade treatment. Two new studies, focusing on pancreatic cancer and tuft cell lung cancer, highlight molecular structures that could become targets for more precise and selective therapies.
Researchers at the Salk Institute have developed a detailed epigenetic catalog of human immune cells, showing how genetics and life experiences influence immune responses differently. The study, published in Nature Genetics, analyzed samples from 110 diverse individuals to distinguish inherited from environmental epigenetic changes. This work could lead to personalized treatments for infectious diseases.
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New research suggests sea turtles possess an epigenetic mechanism that helps maintain balanced sex ratios despite rising temperatures from global warming. This adaptation could mitigate fears of population collapse due to excessive female hatchlings. Scientists from Queen Mary University of London led the study on loggerhead turtles.