A new analysis of clinical trials indicates that semaglutide, the active ingredient in Ozempic and Wegovy, helps older adults with obesity lose substantial weight and improve heart health markers. The findings come from data on participants aged 65 and above who received the once-weekly medication alongside lifestyle changes.
Researchers led by Prof Luca Busetto at the University of Padova examined results from the STEP 1, 3, 4, 5, 8 and 9 trials. The analysis focused on 358 adults aged 65 or older with obesity but without diabetes. Of these, 248 took semaglutide 2.4 mg while 110 received a placebo over 68 weeks.