Illustration of Buffalo Bills predicted to cover spread against Miami Dolphins in NFL Week 10, showing quarterback Josh Allen in action with a 35-23 scoreboard.
Illustration of Buffalo Bills predicted to cover spread against Miami Dolphins in NFL Week 10, showing quarterback Josh Allen in action with a 35-23 scoreboard.
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Model predicts Bills cover spread against Dolphins in Week 10

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SportsLine's advanced computer model, which simulates every NFL game 10,000 times, is backing the Buffalo Bills to cover as 9.5-point favorites against the Miami Dolphins in Week 10. The Bills, with the NFL's top-ranked offense averaging 385.5 yards per game, have dominated recent meetings, winning their last seven against Miami. The model projects a 35-23 victory for Buffalo in 60% of simulations.

Betting Preview

The NFL Week 10 matchup features the Bills (6-2) visiting the Dolphins (2-7) on Sunday, November 9, at 1 p.m. ET from Hard Rock Stadium, airing on CBS and streaming on Paramount+. Buffalo is favored by 9.5 points with a total of 50 points, according to consensus odds. The Bills recently defeated the Kansas City Chiefs 28-21, where Josh Allen completed 23 of 26 passes for 273 yards and one touchdown, plus two rushing scores. James Cook added 114 rushing yards on 27 carries and is cleared to play despite an ankle issue.

Miami is struggling, losing four of their last five games, including a 28-6 defeat to the Baltimore Ravens on October 30. The Dolphins parted ways with general manager Chris Grier after the loss and have scored just six points in two of their last three games. Tua Tagovailoa performs better at home, but the team's offense ranks low recently.

Model Insights

The model, up over $7,000 on top-rated picks since inception and on a 47-29 run since 2024, has Buffalo covering in 60% of simulations and winning outright in 73%. It projects 36-22 on average, with the Over hitting in 63% of cases. Buffalo leads the NFL in rushing at 161.5 yards per game and total offense.

Other Week 10 highlights include the Seahawks (-6.5) covering versus the Cardinals in 56% of simulations, after Sam Darnold's 330-yard, four-touchdown performance last week. Seattle has won eight straight against Arizona. The model also favors Under 49.5 points in 49ers vs. Rams, projecting 45 combined points in 63% of simulations, following their October 2 overtime game totaling 49 points.

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Updating our Steelers-Dolphins coverage: Pittsburgh (7-6) enters atop the AFC North after a 27-22 thriller over Baltimore, hosting streaking Miami (6-7, six straight Ws capped by 34-10 rout of Jets) in chilly 25°F conditions on MNF—where SportsLine projects 46 total points and spots spread value amid key absences.

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In the pivotal Week 16 of the 2025 NFL season—with clinching opportunities for multiple teams detailed in our prior coverage—CBS Sports and SportsLine experts deliver predictions and best bets. Odds via DraftKings Sportsbook feature spreads like Bills (-10) vs. Browns and Ravens (-3) vs. Patriots on Sunday Night Football.

As the 2026 NFL playoffs begin with Wild Card Weekend, projection models have outlined the most favorable routes for each AFC and NFC team to reach Super Bowl LX in Santa Clara on February 8. The Denver Broncos and Seattle Seahawks lead as top seeds with strong simulation odds, while underdogs like the Houston Texans emerge as dark horses based on championship trends. Analysts highlight quarterback performances and matchup advantages as key factors in the wide-open tournament.

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The Cleveland Cavaliers face the Charlotte Hornets in an Eastern Conference matchup on Monday, December 22, with Cleveland favored by 9.5 points. SportsLine's projection model, after 10,000 simulations, leans toward the under on the total of 239.5 points. Injuries to key players on both sides could influence the game's pace.

SportsLine's projection model recommends the Los Angeles Clippers to cover the +4.5 spread versus the Denver Nuggets in Thursday's NBA game. The model, which simulates each matchup 10,000 times, projects Kawhi Leonard to lead the Clippers with 30.5 points. This pick forms part of a three-leg parlay offering over +450 payout potential.

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The New England Patriots, riding a seven-game winning streak at 8-2, host the New York Jets (2-7) on Thursday Night Football in Week 11. New England enters as 12.5-point favorites with an over-under of 43.5 points at Gillette Stadium. The matchup features quarterback Drake Maye against Justin Fields in a rivalry where the Patriots lead the all-time series 75-56-1.

 

 

 

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