Illustration of Buffalo Bills predicted to cover spread against Miami Dolphins in NFL Week 10, showing quarterback Josh Allen in action with a 35-23 scoreboard.
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Model predicts Bills cover spread against Dolphins in Week 10

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SportsLine's advanced computer model, which simulates every NFL game 10,000 times, is backing the Buffalo Bills to cover as 9.5-point favorites against the Miami Dolphins in Week 10. The Bills, with the NFL's top-ranked offense averaging 385.5 yards per game, have dominated recent meetings, winning their last seven against Miami. The model projects a 35-23 victory for Buffalo in 60% of simulations.

Betting Preview

The NFL Week 10 matchup features the Bills (6-2) visiting the Dolphins (2-7) on Sunday, November 9, at 1 p.m. ET from Hard Rock Stadium, airing on CBS and streaming on Paramount+. Buffalo is favored by 9.5 points with a total of 50 points, according to consensus odds. The Bills recently defeated the Kansas City Chiefs 28-21, where Josh Allen completed 23 of 26 passes for 273 yards and one touchdown, plus two rushing scores. James Cook added 114 rushing yards on 27 carries and is cleared to play despite an ankle issue.

Miami is struggling, losing four of their last five games, including a 28-6 defeat to the Baltimore Ravens on October 30. The Dolphins parted ways with general manager Chris Grier after the loss and have scored just six points in two of their last three games. Tua Tagovailoa performs better at home, but the team's offense ranks low recently.

Model Insights

The model, up over $7,000 on top-rated picks since inception and on a 47-29 run since 2024, has Buffalo covering in 60% of simulations and winning outright in 73%. It projects 36-22 on average, with the Over hitting in 63% of cases. Buffalo leads the NFL in rushing at 161.5 yards per game and total offense.

Other Week 10 highlights include the Seahawks (-6.5) covering versus the Cardinals in 56% of simulations, after Sam Darnold's 330-yard, four-touchdown performance last week. Seattle has won eight straight against Arizona. The model also favors Under 49.5 points in 49ers vs. Rams, projecting 45 combined points in 63% of simulations, following their October 2 overtime game totaling 49 points.

Makala yanayohusiana

Dramatic snowy NFL stadium scene of Bills vs. Seahawks highlighting Week 17 playoff stakes.
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NFL week 17 preview highlights playoff implications

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The NFL's penultimate regular-season week on December 28 features high-stakes games that could reshape the playoff picture. With divisions like the AFC East and NFC West on the line, teams such as the Buffalo Bills and Seattle Seahawks aim to secure seeding advantages amid injury challenges.

Updating our Steelers-Dolphins coverage: Pittsburgh (7-6) enters atop the AFC North after a 27-22 thriller over Baltimore, hosting streaking Miami (6-7, six straight Ws capped by 34-10 rout of Jets) in chilly 25°F conditions on MNF—where SportsLine projects 46 total points and spots spread value amid key absences.

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In the pivotal Week 16 of the 2025 NFL season—with clinching opportunities for multiple teams detailed in our prior coverage—CBS Sports and SportsLine experts deliver predictions and best bets. Odds via DraftKings Sportsbook feature spreads like Bills (-10) vs. Browns and Ravens (-3) vs. Patriots on Sunday Night Football.

The Buffalo Bills staged a dramatic comeback from a 21-point deficit to defeat the New England Patriots in Week 15, preserving their chances at the AFC East title. Quarterback Josh Allen delivered a standout performance, leading five straight touchdown drives in the second half. The win thrust Allen into the NFL MVP conversation as the Bills improved their record.

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Pittsburgh's defense is severely depleted without T.J. Watt, who underwent surgery for a partially collapsed lung, plus absences of James Pierre, Andrus Peat, and Derrick Harmon, as the Steelers host a surging Miami on Monday Night Football amid playoff stakes and sub-freezing temps.

The Philadelphia Eagles secured a narrow 13-12 victory over the Buffalo Bills in NFL Week 17 action at Highmark Stadium. Despite a scoreless second half offensively, Philadelphia's defense held firm to preserve the win, impacting playoff seeding for both teams. Josh Allen's late touchdown and failed two-point conversion sealed the outcome.

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