Tenaya Therapeutics publishes RIDGE-1 data on TN-401 gene therapy

Tenaya Therapeutics, Inc. released a slide deck on May 17, 2026, covering results from its RIDGE-1 Phase Ib/II trial of TN-401 gene therapy. The presentation focuses on treatment for PKP2-associated arrhythmogenic right ventricular cardiomyopathy.

The slide deck was issued by the company in connection with the clinical data review. It provides details on the ongoing study of the gene therapy candidate under the ticker TNYA on NASDAQ. No additional outcomes or participant numbers were specified in the release materials.

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Clinical illustration of nurse giving single-dose zilebesiran injection to hypertension patient, with blood pressure monitor showing reduction from KARDIA-2 trial results.
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Single-dose zilebesiran as add-on therapy lowers systolic blood pressure in KARDIA-2 trial

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A single, under-the-skin dose of the investigational RNA-interference drug zilebesiran lowered blood pressure when added to standard therapy in adults whose hypertension remained uncontrolled, according to results from the global Phase 2 KARDIA-2 trial of 663 participants published in JAMA.

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