Confirmed H3N2 K subclade cases emerge in Argentina amid accelerated vaccination plans

Following initial detections in neighboring South American countries, the H3N2 influenza A K subclade has now reached Argentina, with confirmed cases in Buenos Aires, Santa Cruz, and Neuquén, including hospitalizations for pneumonia. Authorities are advancing the 2026 flu vaccination campaign for at-risk groups, while current vaccines offer partial protection against severe illness, bolstered by antivirals like oseltamivir.

Building on earlier confirmations of the H3N2 K subclade in Chile, Peru, Colombia, and other regional nations, Argentina has now reported its first cases, verified through genetic sequencing at the Instituto Malbrán.

The infections include a 5-year-old child in Buenos Aires, two teenagers in Santa Cruz, and in Neuquén, a minor and an adult both hospitalized with pneumonia but who have recovered. This variant's higher transmissibility has prompted swift action.

Though not more lethal than typical H3N2, it spreads more efficiently, with symptoms such as high fever (>39°C), severe fatigue, persistent cough, headache, and in children, gastrointestinal distress.

Health officials are considering starting the 2026 vaccination drive earlier than the usual March-April for vulnerable groups: children under 2, adults over 65, pregnant women, healthcare workers, and those with comorbidities, pending production logistics. Neuquén Health Minister Martín Regueiro emphasized vigilance without alarm.

The existing vaccine provides protection against severe outcomes, and oseltamivir is advised for high-risk patients. Seek immediate care for breathing issues or chest pain.

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Woman in hospital bed at Barcelona clinic appearing healthy after negative hantavirus test
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Woman isolated in Barcelona tests negative in second hantavirus PCR

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The woman under observation at Barcelona's Hospital Clínic after contact with a hantavirus case has tested negative in her second PCR. Sources from the Generalitat's Health Department report she remains asymptomatic and in good general health.

Most Brazilian states report severe acute respiratory syndrome (SRAG) at alert, risk, or high-risk levels, according to Fiocruz's InfoGripe bulletin released on April 29. Cases are driven mainly by influenza A and respiratory syncytial virus (RSV), which circulate more in autumn and winter. Exceptions are Rio de Janeiro, São Paulo, and Rio Grande do Sul.

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Chile's National Service for Disaster Prevention and Response (Senapred) has declared a preventive early alert in the Araucanía Region after detecting highly pathogenic H5N1 avian influenza in backyard birds in Reinaco commune. The measure addresses a zoosanitary risk reported by the Agricultural and Livestock Service (SAG), amid a national emergency. The virus has now reached five regions.

Health authorities in Paraná confirmed two hantavirus cases this year on Friday, both unrelated to the outbreak under investigation on a cruise ship monitored by the WHO.

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The meningitis outbreak in Canterbury, Kent, UK, has escalated with 29 infections and two deaths, prompting mass vaccinations and antibiotics distribution. Authorities warn of possible spread beyond Kent, while Swedish experts advise vigilance.

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