Skin Cancer
Lower-dose ipilimumab regimen linked to better melanoma outcomes in Swedish study
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Researchers at Karolinska Institutet report that using a reduced dose of ipilimumab together with nivolumab in immunotherapy for advanced malignant melanoma was associated with better tumor control and fewer serious side effects than the traditional full-dose combination. In a real-world study of nearly 400 patients with advanced, inoperable skin cancer, response rates and survival times were higher in the lower-dose group, according to results published in the Journal of the National Cancer Institute.
Scientists at UCLA have engineered a new form of zinc oxide for mineral sunscreens that delivers SPF 30 protection while leaving less noticeable residue on skin. The approach reshapes particles into microscopic tetrapods to address a common barrier to regular use.
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A new study reports that using tanning beds is associated with nearly triple the risk of melanoma and with pervasive DNA damage across the skin, including in areas that are usually protected from the sun. Researchers from Northwestern University and the University of California, San Francisco, examined medical records and carried out genomic analyses to reach these conclusions. The findings, published on December 12 in Science Advances, are prompting calls for stronger public health warnings against indoor tanning.