Chronic Pain
Healthy habits may make the brain appear up to eight years younger, study finds
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Researchers at the University of Florida report that lifestyle factors such as optimism, good-quality sleep and strong social support are linked to brains that appear as much as eight years younger than expected for a person’s age. The effect was observed even among adults living with chronic pain, underscoring how everyday behaviors may influence brain health over time.
A comprehensive review of clinical trials suggests that cannabis products high in THC may provide modest, short-term relief for chronic pain, especially neuropathic types, but with notable side effects. In contrast, CBD-dominant products offer no clear advantages. Researchers call for more long-term studies to assess safety and efficacy.
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Preclinical research from McGill University indicates that peripheral nerve injuries can cause long-term changes in the immune system across the body, with distinct patterns in male and female mice. Male mice showed strong and persistent inflammatory responses in the blood, while females did not show the same increase, yet serum from both sexes transmitted pain hypersensitivity when transferred to healthy mice. The findings point to previously unrecognized pathways involved in chronic pain and may open the door to more personalized treatments.