Health ministry confirms detection of H3N2 sub-clade K supergripe in Chile

Chile's Ministry of Health, through the Public Health Institute, confirmed the detection of the first cases of influenza A (H3N2) sub-clade K, known as “supergripe”, in analyzed samples in the country. This finding was expected given the virus's global behavior, already detected in Brazil and Peru. Health Minister Ximena Aguilera clarified that it is not a new virus or a pandemic.

The Ministry of Health (Minsal) reported that the sub-clade K of influenza A (H3N2), nicknamed “supergripe”, has reached Chile after its detection in local samples by the Public Health Institute (ISP). This announcement was made on December 18, 2025, amid a sustained decline in influenza activity in the country.

Health Minister Ximena Aguilera explained that H3N2 has been circulating worldwide for decades and that sub-clade K is a new variant that evades prior antibodies, allowing reinfections. “It is not a pandemic virus,” she emphasized, noting that it does not present more severe symptoms than regular influenza, though it advances outbreaks. The virus emerged in August, likely in Oceania, and spread to Japan and the northern hemisphere, recently reaching Peru and Brazil. Given its person-to-person transmission, its arrival in Chile was probable.

More positive cases are expected to be identified in the coming days as pending sequencing analyses are completed. Minsal reiterates the importance of influenza vaccination for at-risk groups: adults over 65, pregnant women, people with chronic diseases, children aged 6 months to 5 years, and healthcare workers. For these, antivirals are recommended in case of infection.

Additionally, basic preventive measures are urged: frequent hand washing, respiratory etiquette, staying home with symptoms, and seeking care for signs of severity. Vaccination remains the primary tool to prevent serious complications, hospitalizations, and deaths from influenza.

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Realistic illustration of Indonesian doctors treating super flu patients in a Bandung hospital, with Java map highlighting affected areas, conveying controlled outbreak.
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Super flu cases detected in Central and West Java

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Central Java's Health Department detected one case of super flu, or influenza A H3N2 subclade K, in Semarang at the end of December 2025. Meanwhile, Hasan Sadikin Hospital in Bandung confirmed 10 cases in West Java from August to November 2025, with one patient dying due to comorbidities. Health officials stress that this is not a new virus and the situation is under control.

Following initial alerts in Europe and the US, the H3N2 influenza 'subclade K' variant is now advancing in Chile, Peru, and Colombia, prompting Argentina to analyze local samples amid concerns of higher infection and hospitalization risks.

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Building on international alerts, Colombia's Ministry of Health confirmed the first case of influenza A(H3N2) subclade K in a traveler with mild symptoms. Officials are monitoring this seasonal variant, with pediatric experts urging enhanced prevention amid peak transmission risks for children.

Influenza has truly arrived in Sweden. In the first week of the year, 2,131 cases were confirmed, a 22 percent increase from the end of the previous week. The spread is assessed as medium-high level, according to the Public Health Agency.

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The United States managed to curb a bird flu outbreak in 2025 after its first known human death from the virus, ending the public health emergency response by July. Despite progress, experts warn that the H5N1 strain remains a threat to animals and could still pose risks to humans. Efforts focused on testing, vaccination research, and biosecurity measures helped reduce cases in livestock and people.

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Hong Kong is approaching the winter flu season, but vaccination rates among most age groups remain below the 70 per cent threshold needed for herd immunity, a leading government medical adviser has warned. David Hui Shu-cheong on Saturday reminded the public to get vaccinated ahead of Lunar New Year, when social gatherings are frequent.

 

 

 

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