Immune System
Cryo-expansion microscopy captures 3D architecture of killer T cells at the immune synapse, including in human tumors
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Researchers from the University of Geneva and Lausanne University Hospital report they have visualized, in three dimensions and under near-native conditions, how cytotoxic T cells organize their killing machinery at the immune synapse. The work, published in Cell Reports, applies cryo-expansion microscopy to human T cells and to tumor tissue samples, providing nanoscale views intended to support immunology and cancer research.
Researchers led by Helmholtz Munich report that some gut-dwelling bacteria — including strains not typically considered harmful — possess syringe-like molecular machinery that can deliver bacterial proteins into human cells, affecting immune and metabolic signaling. The work also links these bacterial “effector” genes to Crohn’s disease–associated microbiome patterns, though the authors say more studies are needed to determine how the mechanism influences disease.
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A recent clinical study shows that HDI Propoelix propolis extract can support the immune system in patients with metabolic disorders such as diabetes, obesity, and hypertension. The 30-day study was conducted at RS Soerojo Magelang and presented at a seminar in Jakarta on March 7, 2026. Experts emphasize that the supplement serves only as a complement, not a replacement for medical therapy.
A study of young female university students in Saudi Arabia has found that symptoms of anxiety and insomnia are associated with reduced levels of natural killer cells, key components of the immune system’s early defense. The findings suggest that psychological stressors may be linked to weaker immune responses, though the research shows correlation rather than causation and is limited to a small, specific population.
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A new study in mice reveals that tattoo ink can lead to chronic inflammation in lymph nodes, potentially altering immune responses for life. Human samples show similar effects years after tattooing. Researchers urge more investigation into health risks.
A new study reveals that decades of endurance exercise, such as running and cycling, may keep the immune system youthful and resilient in older adults. Researchers found that natural killer cells in trained individuals functioned better, showed lower inflammation, and resisted fatigue under stress. The findings suggest physical activity trains the immune system much like it does muscles.