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Study links lysosomal ion channel TMEM175 to protection against over-acidification, with implications for Parkinson’s research
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Researchers at LMU Munich, Bonn-Rhein-Sieg University of Applied Sciences, TU Darmstadt and Nanion Technologies report that the lysosomal ion channel TMEM175 helps prevent excessive acidification inside lysosomes, a malfunction that the team says could contribute to toxic buildup associated with Parkinson’s disease. The findings were reported in the Proceedings of the National Academy of Sciences.
Researchers have found that vivid, immersive dreams can make sleep feel deeper and more restorative, even during periods of high brain activity. A study analyzing brain recordings from 44 healthy adults showed that participants reported their deepest sleep after intense dream experiences. The findings challenge traditional views of deep sleep as minimal brain activity.
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Researchers analyzing immune cells from people with long COVID have identified a distinct molecular state in CD14+ monocytes—labeled “LC-Mo”—that was more prevalent among patients whose initial COVID-19 illness was mild to moderate and that tracked with reported fatigue and respiratory symptoms, along with higher levels of inflammatory signaling molecules in blood plasma.
Archaeologists have identified the oldest genetically confirmed dog remains from a site in Turkey dating back 15,800 years, pushing the timeline for canine domestication by about 5,000 years. Additional remains from the UK, around 14,300 years old, show dogs were widespread across Europe during the hunter-gatherer era. The findings suggest early humans spread domesticated dogs through cultural exchanges.
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Astronomers have identified a hidden white dwarf companion as the source of extreme X-rays from the naked-eye star Gamma Cassiopeiae. Observations from Japan's XRISM space telescope revealed the companion's orbital motion through shifting plasma velocities. The discovery confirms a long-predicted class of binary star systems.
Researchers have documented sperm whales colliding head-on with their heads for the first time using drone footage from the Azores and Balearic islands. The behavior, observed among sub-adult whales, supports longstanding sailor accounts of aggressive whale encounters. The findings were published on March 23 in Marine Mammal Science.
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NASA's Space Launch System (SLS) rocket is set to launch Artemis II as soon as April 1, 2026, sending four astronauts on a crewed flyby to the Moon's far side—the farthest from Earth any humans have traveled. This follows February's Artemis program adjustments addressing SLS delays, using the rocket's powerful core stage and boosters detailed ahead of liftoff.
Benzene leaks from gas cookers exceed safety limits in European homes
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