Antibiotic Resistance
Global genomic study finds highly diverse E. coli strains in diabetic foot infections, including drug-resistant lineages
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A genomic analysis of Escherichia coli isolated from infected diabetic foot ulcers across 10 countries found no single dominant strain, instead revealing wide genetic diversity and a subset of isolates with markers of multidrug or extensive drug resistance, researchers from King’s College London and the University of Westminster report.
Researchers in Guatemala's Western Highlands discovered a stark mismatch between public perceptions of drinking water safety and actual contamination levels. Bottled water, widely trusted as the safest option, proved most prone to harmful bacteria, while protected municipal wells emerged as the cleanest sources. The findings, published in the Journal of Water and Health, underscore risks to public health from unsafe water.
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Researchers from New England Biolabs and Yale University have developed the first fully synthetic system for engineering bacteriophages targeting Pseudomonas aeruginosa, a major antibiotic-resistant bacterium. Published in PNAS, the method uses digital DNA sequences to build viruses from scratch, bypassing traditional challenges in phage modification. This innovation aims to accelerate therapies against global antibiotic resistance threats.