Biochemistry
Mayo Clinic team uses DNA aptamers to tag senescent ‘zombie’ cells
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Researchers at Mayo Clinic have developed an aptamer-based technique to tag senescent, or so‑called “zombie,” cells in living mouse tissues, work they say could eventually support targeted therapies for age‑related diseases. The project grew out of a chance conversation between two graduate students, according to Mayo Clinic.
Researchers have reconstructed a nitrogen-fixing enzyme from more than three billion years ago using synthetic biology. The work offers new insights into how life evolved on early Earth and could inform searches for life elsewhere in the universe.
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Researchers at The University of Osaka have developed ultra-small pores in silicon nitride membranes that approach the scale of natural ion channels. These structures enable repeatable opening and closing through voltage-controlled chemical reactions. The advance could aid DNA sequencing and neuromorphic computing.