As AFCON 2025 kicks off in Morocco—with 32 Premier League players absent, hitting Sunderland hardest (six losses) while sparing Arsenal—clubs face varying fixture difficulties and adaptation challenges. Previously covered absences now test teams like Manchester United amid packed schedules.
Building on initial reports of AFCON 2025's toll on Premier League squads (32 players from 14 nations absent until at least January 18), the tournament opener this Sunday between hosts Morocco and Comoros underscores immediate challenges for affected clubs.
Sunderland, losing six players (including Noah Sadiki, Reinildo—key to five clean sheets, notably the recent Wear-Tyne derby—plus Chemsdine Talbi and Bertrand Traore, totaling 4,412 minutes), must maintain their strong start. Manchester United (Bryan Mbeumo, Amad Diallo, Noussair Mazraoui), Fulham (Alex Iwobi, Calvin Bassey, Samuel Chukwueze), and Burnley (Lyle Foster, Hannibal Mejbri, Axel Tuanzebe) each lose three, costing over 3,000 minutes and significant attacking threat—United and Fulham 11 goal involvements each, Everton eight (mainly Iliman Ndiaye), Liverpool seven (Mohamed Salah).
Fixture schedules amplify pressures: Aston Villa faces the toughest next six games despite no absences, while Liverpool has the easiest. Manchester United's recent 4-4 draw with Bournemouth prompted manager Ruben Amorim's first switch to a back four, potentially adapting to missing wing-backs from his 3-4-2-1 system. This weekend's matches will reveal early coping strategies for teams like Sunderland and Liverpool.