Alzheimer's Disease
NAU researchers test non-invasive blood method for early Alzheimer’s detection
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Scientists at Northern Arizona University are developing a non-invasive blood test that could help detect Alzheimer’s disease before symptoms appear by examining how the brain uses glucose through tiny blood-borne microvesicles. Led by assistant professor Travis Gibbons and supported in part by the Arizona Alzheimer’s Association, the project aims to enable earlier diagnosis and intervention, similar to how doctors manage cardiovascular disease.
Researchers at UNSW Sydney have identified around 150 functional DNA enhancers in human astrocytes that regulate genes associated with Alzheimer's disease. By testing nearly 1,000 potential switches using advanced genetic tools, the team revealed how non-coding DNA influences brain cell activity. The findings, published on December 18 in Nature Neuroscience, could aid in developing targeted therapies and improving AI predictions of gene control.
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New research finds that blood biomarkers associated with Alzheimer’s disease increase significantly faster in people with obesity than in those without. Drawing on five years of data from 407 volunteers, the study suggests that blood tests can detect obesity‑related changes earlier than brain scans, underscoring obesity as a major modifiable risk factor for Alzheimer’s.