Abatacept delays rheumatoid arthritis for years after treatment

A one-year course of the drug abatacept can delay the onset of rheumatoid arthritis by up to four years in high-risk individuals. The benefits persisted long after treatment stopped, according to new research from King's College London.

The study, published in The Lancet Rheumatology, followed participants from an earlier trial for four to eight years. Researchers tracked 213 people from the UK and the Netherlands who were at high risk of developing rheumatoid arthritis. Those who received abatacept developed the condition much later than those on placebo, with some delays extending several years beyond the treatment period.

相关文章

A doctor giving an injection to a patient in a clinic with brain scans in the background, illustrating a trial on immune drug for depression.
AI 生成的图像

Small JAMA Psychiatry trial suggests immune-targeting drug may help some treatment-resistant depression symptoms

由 AI 报道 AI 生成的图像 事实核查

A proof-of-concept randomized clinical trial published online May 20, 2026, in JAMA Psychiatry found signals that tocilizumab—an anti-inflammatory drug used for immune-mediated conditions including rheumatoid arthritis—may improve some symptoms in adults with moderate-to-severe depression who had a poor response to antidepressants and evidence of low-grade inflammation.

Researchers at the University of Colorado Boulder have demonstrated that a single injected drug-delivery system can reverse osteoarthritis in animals within weeks. The team, led by chemical and biological engineer Stephanie Bryant, reported success in early animal experiments. They aim to advance to human trials after further safety testing.

由 AI 报道

Promising animal studies from University of Colorado Boulder offer hope for osteoarthritis patients through a single injection that repairs damaged joints in weeks. Affecting one in six people over 30—with no cure—the disease limits daily activities, but this therapy targets root causes beyond pain management or surgery.

Researchers at Aarhus University report that the hormone GLP-1—mimicked by drugs such as Wegovy—can be measured in the joint fluid of patients with inflammatory arthritis, but only at very low levels. The findings, published in The Lancet Rheumatology, suggest GLP-1–based medicines might eventually be studied for potential direct effects on joint inflammation, though the researchers say clinical trials are needed to show whether such treatment works.

由 AI 报道

A new combination pill containing bictegravir and lenacapavir shows promise for people with HIV who require complex regimens. The phase three ARTISTRY 1 study found it performed as well as existing multi-pill options. Experts note its impact in South Africa will likely remain limited.

此网站使用 cookie

我们使用 cookie 进行分析以改进我们的网站。阅读我们的 隐私政策 以获取更多信息。
拒绝