Thymus health may predict longevity and cancer outcomes

New research from Mass General Brigham shows that the thymus, a small organ once thought irrelevant in adults, strongly influences lifespan and disease risk. Using AI on CT scans, scientists linked better thymic health to lower risks of death and cancer progression.

Researchers examined CT scans from more than 25,000 adults in a lung cancer screening trial and over 2,500 participants in the Framingham Heart Study. They developed a thymic health score based on the organ's size, structure, and composition. Adults with higher scores had about a 50 percent lower risk of death from any cause, a 63 percent lower risk of cardiovascular death, and a 36 percent lower risk of lung cancer.

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