For decades diabetes diagnosis has depended on blood sugar measurements crossing a set threshold. Researchers now worry this method misses millions of people already developing the disease. Better detection tools are in development to address these shortcomings.
Doctors have long relied on blood glucose levels to identify diabetes risk. The approach works for many but falls short in certain populations where the disease progresses without clear blood sugar spikes.
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A new Karolinska Institutet study finds that children with moderate obesity face higher risks of type 2 diabetes, high blood pressure, and lipid disorders in adulthood, even without apparent risk markers. Researchers urge treatment for all such children.
New research published in Nature Medicine reveals that people with prediabetes can normalize blood sugar levels without losing weight. About one in four participants in lifestyle programs achieved this remission, offering protection against diabetes similar to weight loss methods. The key factors involve fat distribution and certain hormones.
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Scientists at Washington University School of Medicine in St. Louis have developed a blood test that estimates when Alzheimer's symptoms may begin, using levels of the protein p-tau217. The model predicts onset within about three to four years, potentially aiding clinical trials and early interventions. This advance relies on data from 603 older adults in ongoing studies.
Researchers at UCL have identified a protein called LRG1 that initiates the earliest damage in diabetic retinopathy, a major cause of vision loss in adults with diabetes. In mouse studies, blocking LRG1 prevented retinal harm and preserved eye function. The findings suggest potential for new preventive treatments targeting this protein.
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New research from the University of Southern California suggests that subtle declines in brain blood flow and oxygen delivery may be early indicators of Alzheimer's disease. The study, published in Alzheimer's and Dementia, used noninvasive scans to connect vascular health with amyloid plaques and hippocampal shrinkage. These findings highlight the role of brain circulation in the disease process beyond traditional markers like amyloid and tau.