Deteksi diabetes memerlukan alat yang lebih baik untuk menangkap kasus sejak dini

Selama beberapa dekade, diagnosis diabetes bergantung pada pengukuran kadar gula darah yang melewati ambang batas tertentu. Para peneliti kini khawatir metode ini melewatkan jutaan orang yang sebenarnya sudah mulai mengidap penyakit tersebut. Alat deteksi yang lebih baik sedang dikembangkan untuk mengatasi kekurangan ini.

Dokter telah lama mengandalkan kadar glukosa darah untuk mengidentifikasi risiko diabetes. Pendekatan ini berhasil bagi banyak orang, namun kurang efektif pada populasi tertentu di mana penyakit tersebut berkembang tanpa adanya lonjakan gula darah yang jelas.

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Pediatrician assessing overweight children in clinic, highlighting study-recommended early treatment to prevent adult risks like diabetes and hypertension.
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Study recommends treatment for all children with obesity

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A new Karolinska Institutet study finds that children with moderate obesity face higher risks of type 2 diabetes, high blood pressure, and lipid disorders in adulthood, even without apparent risk markers. Researchers urge treatment for all such children.

New research published in Nature Medicine reveals that people with prediabetes can normalize blood sugar levels without losing weight. About one in four participants in lifestyle programs achieved this remission, offering protection against diabetes similar to weight loss methods. The key factors involve fat distribution and certain hormones.

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Scientists at Washington University School of Medicine in St. Louis have developed a blood test that estimates when Alzheimer's symptoms may begin, using levels of the protein p-tau217. The model predicts onset within about three to four years, potentially aiding clinical trials and early interventions. This advance relies on data from 603 older adults in ongoing studies.

Researchers at UCL have identified a protein called LRG1 that initiates the earliest damage in diabetic retinopathy, a major cause of vision loss in adults with diabetes. In mouse studies, blocking LRG1 prevented retinal harm and preserved eye function. The findings suggest potential for new preventive treatments targeting this protein.

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New research from the University of Southern California suggests that subtle declines in brain blood flow and oxygen delivery may be early indicators of Alzheimer's disease. The study, published in Alzheimer's and Dementia, used noninvasive scans to connect vascular health with amyloid plaques and hippocampal shrinkage. These findings highlight the role of brain circulation in the disease process beyond traditional markers like amyloid and tau.

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