Research
Study links speech learning and memory to auditory and somatosensory cortex, not motor cortex
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A study by researchers at McGill University and Yale School of Medicine suggests that learning—and later retaining—new speech patterns depends more on brain areas that process sound and bodily sensation than on the motor cortex regions that control speech movements. The work was published in the Proceedings of the National Academy of Sciences.
A study from the Monell Chemical Senses Center reports that, calorie for calorie, fructose and glucose engage different gut–brain pathways in mice. The researchers found glucose more strongly suppresses activity in hunger-related AgRP neurons, while fructose produces a weaker effect through a pathway involving the gut hormone PYY and signaling via the vagus nerve.
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A study has identified how an existing medication could improve immunotherapy outcomes for fibrolamellar carcinoma. The rare liver cancer currently has no cure and often spreads before detection. Researchers demonstrated the approach using patient tumor samples.
Researchers have identified a rare genetic mutation that may help people from long-lived families stay healthier longer by reducing harmful inflammation. The findings were presented at the European Society of Human Genetics conference in Gothenburg.
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Researchers at Baylor College of Medicine report that tubulin—the building block of microtubules—can shift Tau and alpha-synuclein inside cellular condensates away from disease-linked aggregation and toward roles that support healthy neurons.
A study in mice has found that transplanting gut microbes from young animals into older ones can restore youthful levels of brain plasticity. The research points to potential new ways of treating conditions that are normally only reversible in childhood.
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Researchers at the University of California, Riverside have proposed that amyloid beta disrupts tau protein function inside neurons, potentially triggering Alzheimer's disease. The findings challenge the focus on external plaques as the primary cause.
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