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Study links parathyroid hormone to reduced chronic low back pain in mice by limiting abnormal nerve growth
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A study published in the journal *Bone Research* reports that parathyroid hormone (PTH) reduced pain-related behaviors in mouse models of spinal degeneration, apparently by strengthening vertebral endplates and triggering bone-cell signals that repel pain-sensing nerve fibers. The work was led by Dr. Janet L. Crane of Johns Hopkins University School of Medicine.
Honey bees perform their waggle dance more precisely when more hive mates watch, according to a new study. Researchers found that dancers adjust their movements to attract followers, sacrificing accuracy for engagement when audiences are small. The findings highlight the social dynamics of bee communication.
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Un team guidato da David Julius, premio Nobel per la Medicina nel 2021, ha descritto il meccanismo molecolare attraverso il quale le cellule a ciuffo intestinali segnalano al cervello di sopprimere l'appetito durante le infezioni parassitarie. Lo studio, pubblicato oggi su Nature, identifica una comunicazione basata su acetilcolina e serotonina che attiva il nervo vago. La scoperta potrebbe favorire lo sviluppo di trattamenti per condizioni come la sindrome dell'intestino irritabile.
Scientists at Arizona State University have identified two unexpected ways bacteria can spread without their usual flagella structures. In one study, E. coli and salmonella use sugar fermentation to create fluid currents for surface migration, dubbed 'swashing.' A separate study reveals a molecular 'gearbox' in flavobacteria that controls directional movement.
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Profamilia presented a study on gender-based violence in Medellín, Cali, Uribia, and Dibulla, gathering input from over 8,500 people. The research shows that 58.4% of girls, boys, and adolescents experienced at least one form of violence in the last year. Accompanying the study is the 'Somos Visibles: Generaciones Sin Violencias' initiative to reach over 9,500 people by 2029.
A new study warns of an interdisciplinary blind spot that could force 132 million people to flee rising sea levels, which could rise by up to 150 centimeters. Swedish oceanographer Ola Kalén at SMHI describes the acceleration of sea level rise since the 1960s as shocking.
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A new study has revealed over 200 metabolic enzymes attached directly to human DNA inside the cell nucleus, challenging traditional views of cellular processes. These enzymes form unique patterns in different tissues and cancers, described as a 'nuclear metabolic fingerprint.' The discovery suggests links between metabolism and gene regulation that may influence cancer development and treatment.
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