Research

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UCSF researcher Jennifer Mitchell in a lab examining MM120, an LSD-based drug for treating generalized anxiety disorder.

UCSF researchers test LSD-based MM120 for generalized anxiety disorder

Heather Vogel AI에 의해 생성된 이미지 사실 확인됨

UCSF neuroscientist Jennifer Mitchell and collaborators are evaluating MM120, a pharmaceutical form of LSD, as a potential treatment for generalized anxiety disorder. A randomized clinical trial published in JAMA found that a single dose reduced anxiety symptoms versus placebo, with benefits persisting up to 12 weeks in the optimal dose group, according to the study and the drug’s sponsor.

Three German hospitals lead in European patent applications

Three German university hospitals rank among Europe's most active research institutions in patent applications. According to a study by the European Patent Office (EPA), these clinics filed numerous patents between 2001 and 2020. Germany holds second place in Europe overall.

Study shows lipids fuel triple-negative breast cancer growth

Heather Vogel

Researchers at the Huntsman Cancer Institute have found that triple-negative breast cancer cells depend on lipids for growth, a process accelerated by obesity-related high lipid levels. In mouse models, reducing these lipids slowed tumor progression, suggesting potential new treatments. The findings warn against high-fat diets like keto for obese breast cancer patients.

Researchers identify limits of quantum computers on exotic matter

Scientists have proven that even advanced quantum computers may fail to identify certain exotic quantum phases of matter, describing it as a 'nightmare scenario.' This finding highlights potential boundaries in quantum computation despite its promises. The research, led by Thomas Schuster at Caltech, connects quantum information science with physics fundamentals.

Scientists identify specific brain cells linked to depression

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Researchers at McGill University and the Douglas Institute have pinpointed two types of brain cells altered in people with depression. Using advanced genomic analysis on post-mortem brain tissue, they found genetic disruptions in excitatory neurons and microglia. The findings, published in Nature Genetics, could lead to more targeted treatments for the condition affecting over 264 million people worldwide.

Ketogenic diet protects young rats from prenatal stress effects

Researchers in Italy have found that a ketogenic diet can shield young rats from the long-term mental and behavioral impacts of prenatal stress. The high-fat, low-carbohydrate regimen, administered after weaning, improved sociability and reduced stress-related issues in the offspring of stressed mothers. These findings, presented at the ECNP conference in Amsterdam, suggest potential early dietary interventions, though human trials are needed.

Research quantifies sycophancy issues in large language models

Two new studies reveal that leading AI models often agree with users' false or inappropriate statements, a behavior known as sycophancy. Researchers from multiple universities developed benchmarks to measure this tendency in both mathematical and social contexts. The findings highlight widespread issues across models, though some perform better than others.

Efficient AI models could reduce energy use by over a quarter

Researchers have found that selecting the most energy-efficient AI models for specific tasks could slash global AI energy consumption by 27.8 percent. This approach would save 31.9 terawatt-hours this year, equivalent to the output of five nuclear reactors. The study highlights a trade-off where outputs are only 3.9 percent less useful.

One in four older adults regain optimal well-being within three years

A University of Toronto study reveals that nearly one in four adults aged 60 and older who started with poor well-being achieved optimal wellness after three years. Factors like physical activity, good sleep, and emotional support were key to recovery. The research highlights the potential for resilience in later life through lifestyle and social factors.

Different depression types tied to distinct physical health risks

New research shows that atypical depression increases diabetes risk, while melancholic depression heightens chances of heart disease. The findings, from a seven-year study of nearly 6,000 adults, highlight the need for tailored mental and physical health approaches. Presented at the ECNP Congress in Amsterdam, the work underscores biological differences in depression subtypes.

Magnetic gel aids efficient kidney stone removal in pig tests

Researchers at Stanford University have developed a magnetic gel that coats kidney stone fragments, allowing for their removal in bulk using a magnetic wire. Tested successfully in pigs, the technique aims to reduce tissue damage and the need for repeated surgeries compared to standard methods. Experts praise it as a promising alternative to current procedures.

Bone density dips during breastfeeding but recovers quickly

Maria Karlsson

A new study from Lund University shows that bone density drops significantly in breastfeeding women, but recovery happens quickly afterward. The research offers a positive surprise and could influence osteoporosis treatments. Findings come from a ten-year follow-up of 750 women.

 

 

 

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