Researchers in Sweden have created insulin-producing cells from human stem cells that reversed diabetes symptoms when transplanted into mice. The cells matured after placement in the eye and maintained glucose regulation for months. The work was published in Stem Cell Reports.
Scientists at Karolinska Institutet developed an improved protocol to derive pancreatic islets from multiple human pluripotent stem cell lines. The method uses refined culture conditions and three-dimensional clusters to reduce unwanted cell types and enhance glucose responsiveness.
