Equipe sueca restaura o controle da glicemia em camundongos diabéticos

Pesquisadores na Suécia criaram células produtoras de insulina a partir de células-tronco humanas que reverteram os sintomas do diabetes após serem transplantadas em camundongos. As células amadureceram após serem colocadas no olho e mantiveram a regulação da glicose por meses. O trabalho foi publicado na Stem Cell Reports.

Cientistas do Karolinska Institutet desenvolveram um protocolo aprimorado para derivar ilhotas pancreáticas a partir de várias linhagens de células-tronco pluripotentes humanas. O método utiliza condições de cultura refinadas e aglomerados tridimensionais para reduzir tipos celulares indesejados e aumentar a resposta à glicose.

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