A recent clinical study shows that HDI Propoelix propolis extract can support the immune system in patients with metabolic disorders such as diabetes, obesity, and hypertension. The 30-day study was conducted at RS Soerojo Magelang and presented at a seminar in Jakarta on March 7, 2026. Experts emphasize that the supplement serves only as a complement, not a replacement for medical therapy.
The 25th clinical study by HDI Propoelix, recently published, explores the benefits of propolis extract for adult patients with metabolic conditions. Conducted at RS Soerojo Magelang, a vertical hospital under Indonesia's Ministry of Health, it involved office workers aged 25-60, including those with obesity and diabetes.
Over 30 days, the research found that propolis supplement use maintains immune system balance without raising inflammation risk. Laboratory examinations showed acute-phase white blood cells more prepared for mild infections, while platelet and neutrophil profiles remained stable, and inflammation indicators did not increase.
At a press conference in Central Jakarta and the National Health Seminar titled 'Beyond the Fundamentals of Propolis Science: Clinical Evidence Behind HDI Propoelix' on Saturday, March 7, 2026, lead researcher Dr. H. Harli Amir Mahmudji, Sp.PD-KEMD, stated, "In chronic patients, the immune system remains balanced and inflammation risk does not increase." He emphasized, "This is a complement, not a replacement for medical therapy."
Dr. Muhamad Sahlan, S.Si., M.Eng., from Universitas Indonesia, added, "Propolis is one of the natural materials with very high complexity of bioactive compounds. The challenge is how to ensure standardization and scientific proof so it can be accepted in modern medical practice. Efforts like those by HDI are important to bridge basic science with clinical applications."
The researchers acknowledged the study's limitations, such as its short duration and limited participants, calling for further research with larger samples. Harli also highlighted the importance of balanced nutritious eating and regular exercise as primary ways to maintain immunity, with supplements serving only as adjuvants.
