Cancer Research
New biomarker improves early lung cancer detection
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Researchers have identified a novel protein biomarker that detects lung cancer at an early stage with high accuracy. The discovery, detailed in a recent study, could enhance screening methods and improve patient outcomes. Clinical trials showed promising results in identifying the disease before symptoms appear.
Researchers develop AI tool for early cancer detection
Scientists have unveiled a new artificial intelligence model that improves early detection of lung cancer from CT scans. The tool, trained on thousands of images, achieves higher accuracy than traditional methods. This advancement could significantly boost survival rates for patients.
Bacteria in tumors produce molecule to boost cancer chemotherapy
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Scientists have identified a molecule produced by bacteria inside tumors that enhances the effectiveness of chemotherapy against colorectal cancer. The compound, 2-methylisocitrate, damages cancer cell DNA and disrupts their metabolism. This discovery could lead to new treatments that make existing drugs more potent.
New compounds halt cancer growth without damaging healthy cells
Scientists from the Francis Crick Institute and Vividion Therapeutics have developed chemical compounds that prevent the RAS gene from signaling tumor growth via the PI3K pathway. The treatment stopped tumor growth in mice models of lung and breast cancer without causing side effects like hyperglycemia. It is now entering human clinical trials.
Research highlights lymph nodes' role in enhancing cancer immunotherapy
New studies reveal that preserving lymph nodes during cancer surgery could improve patient responses to immunotherapy by supporting key immune cells. Led by the Peter Doherty Institute, the research emphasizes lymph nodes' crucial function in training T cells to fight tumors. The findings, published in Nature Immunology, suggest rethinking surgical practices to boost treatment effectiveness.
DNA scar catalog opens paths to overcome cancer drug resistances
Researchers at Spain's National Cancer Research Centre (CNIO) have developed a comprehensive catalog of mutational 'scars' in DNA caused by cancer. This breakthrough, published in Nature, could help bypass resistances to treatments like PARP inhibitors. The study analyzes thousands of tumor samples to identify key genetic patterns.