Obesity
Weight-loss drugs show early promise for alcohol and other addictions, review finds
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Medications such as semaglutide (marketed as Ozempic/Wegovy) could aid treatment of alcohol and other substance use disorders, according to a peer‑reviewed review in the Journal of the Endocrine Society. Early animal and human data suggest these GLP‑1 receptor agonists act on brain reward circuits; lead author Lorenzo Leggio urged caution, saying, “Early research in both animals and humans suggests that these treatments may help reduce alcohol and other substance use.”
Study highlights disparities in obesity care access
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A recent analysis reveals significant gaps in obesity treatment for certain demographic groups in the United States. Researchers found that access to care varies widely based on race, income, and location, underscoring ongoing challenges in healthcare equity.
Study links prediabetes remission to lower diabetes risk without weight loss
Researchers in Tübingen have found that people with prediabetes can reduce their risk of developing type 2 diabetes by 71% through lifestyle changes that normalize blood sugar levels, even if they do not lose weight. The study emphasizes the role of improved fat distribution over mere weight reduction. This challenges current guidelines focused primarily on shedding pounds.
Study shows lipids fuel triple-negative breast cancer growth
Researchers at the Huntsman Cancer Institute have found that triple-negative breast cancer cells depend on lipids for growth, a process accelerated by obesity-related high lipid levels. In mouse models, reducing these lipids slowed tumor progression, suggesting potential new treatments. The findings warn against high-fat diets like keto for obese breast cancer patients.
Running reverses junk food's depressive effects in rats
New research from University College Cork shows that voluntary exercise can counteract the mood-damaging impacts of a high-fat, high-sugar diet in rats. The study highlights specific gut metabolites and hormones that explain these benefits. However, poor diet still limits brain neurogenesis despite exercise.
Hidden fat damages arteries even in seemingly healthy people
Researchers at McMaster University have discovered that visceral fat around organs and fat in the liver can silently harm arteries, increasing stroke and heart attack risks, regardless of outward appearance. The study, involving MRI scans of over 33,000 adults, challenges the reliability of BMI for assessing cardiovascular health. Published on October 17, 2025, the findings urge a shift toward imaging-based evaluations.
Study connects ultra-processed foods to brain changes
An international study of nearly 30,000 people has linked frequent consumption of ultra-processed foods to differences in brain structure. These changes may contribute to overeating and food addiction, though causation remains unproven. Researchers emphasize the need for further evidence on how food additives affect the brain.