Медицинские исследования
Study identifies SLAMF6 as a self-activating brake on anti-cancer T cells, pointing to a new immunotherapy target
Сообщено ИИ Изображение, созданное ИИ Проверено фактами
A research team led by Université de Montréal immunologist André Veillette reports that the immune receptor SLAMF6 can inhibit T cells by activating through interactions on the T cell surface itself, a mechanism the authors say could help explain why some patients fail to respond—or later stop responding—to checkpoint-based cancer immunotherapies. In the same study, the researchers describe monoclonal antibodies designed to block SLAMF6’s self-interaction, which boosted T-cell activity in laboratory tests and strengthened anti-tumor responses in mouse experiments.
A copper-based drug has shown potential to reduce toxic protein buildup and improve memory in laboratory models of Alzheimer’s disease. Researchers at Monash University found that the compound Cu(ATSM) enhanced the brain’s waste-clearing mechanisms. The results were published in ACS Chemical Neuroscience.
Сообщено ИИ
Шахматы заняли важное место на клиническом симпозиуме по технологиям нейрокомпьютерных интерфейсов, прошедшем в Шэньчжэне. Казначей ФИДЕ Чжу Чэнь посетила мероприятие, подчеркнув потенциал игры в развитии медицинских исследований.
A study of 440 participants from the Women’s Interagency HIV Study found that accelerated epigenetic aging in monocytes—an immune cell type—tracked more closely with emotional and cognitive depression symptoms such as hopelessness and loss of pleasure than with physical symptoms like fatigue. The work, published in The Journals of Gerontology: Series A, adds evidence that cell-type-specific aging measures could contribute to future biological tools to complement symptom-based depression screening, though researchers say more validation is needed before clinical use.
Сообщено ИИ Проверено фактами
Engineers at Washington University in St. Louis report that while single abnormal cells can mechanically probe roughly 10 microns beyond what they directly touch, groups of epithelial cells can combine forces through collagen to sense features more than 100 microns away—an effect the researchers say could help explain how cancer cells navigate tissue.
A study shows that advanced lung cancer patients receiving immunochemotherapy earlier in the day survive longer. A Hong Kong medical expert says the discovery opens possibilities for optimal treatment times, though more research is needed. The research was led by academics from Hunan Cancer Hospital in mainland China and supported by the Chinese University of Hong Kong’s faculty of medicine.
Сообщено ИИ
Researchers in Brazil have uncovered how pancreatic cancer uses a protein called periostin to invade nerves and spread early. This discovery explains the disease's aggressiveness and suggests new treatment targets. The findings, published in Molecular and Cellular Endocrinology, highlight the tumor's ability to remodel surrounding tissue.
Researchers test electricity-based method to reshape the cornea for vision correction
28 мая 2026, 21:50Penn researchers identify immune protein GPNMB as potential target to slow Parkinson’s-related pathology spread
20 мая 2026, 20:53Study finds alzheimer's risk factors hit women harder
17 мая 2026, 23:35Scientists find MYC protein helps cancers resist chemotherapy
16 мая 2026, 23:05Hidden tooth-root infections may be linked to poorer blood sugar control, studies suggest
13 марта 2026, 04:30Study links dual colon polyps to higher risk of advanced precancerous changes
08 марта 2026, 06:38PET brain scans link ketamine’s rapid antidepressant effect to shifts in AMPA receptor availability
25 февраля 2026, 03:13UCLA study finds five-day accelerated TMS schedule performed similarly to conventional six-week course for treatment-resistant depression
24 февраля 2026, 06:42Study links brain blood flow changes to Alzheimer's risk
15 февраля 2026, 20:58Study links sympathetic nerve signaling to early pancreatic cancer growth via a fibroblast feedback loop