Alexandre Muller withdrew from his French Open first-round match against Stefanos Tsitsipas on Tuesday after suffering a calf injury.
The 29-year-old Frenchman began the match on Philippe Chatrier court by holding serve and breaking early. He then lost the next nine games in a row, dropping the first set 6-2 and falling behind 3-0 in the second set. Muller requested a medical timeout and returned briefly before shaking hands with Tsitsipas and leaving the court in tears.
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Jannik Sinner lost to Juan Manuel Cerundolo in the second round of the French Open on May 28. The world No. 1 led by two sets before physical issues forced him off court. The defeat ended his 30-match winning streak.
David Goffin secured a straight-sets victory in the first round of French Open qualifying on May 18 and struggled to hold back tears during his post-match interview. The 35-year-old Belgian defeated Tseng Chun-hsin 6-3, 6-1 in 73 minutes at Court Suzanne-Lenglen. The emotional moment came as the crowd gave him a standing ovation and chanted his name.
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Corentin Moutet lost his first-round match at Wimbledon after smashing his racket on his knee three times in frustration. Marcos Giron defeated the Frenchman 4-6, 6-4, 7-5, 6-4 on June 30.
Arthur Fils retired after four games in his first-round match at the Italian Open on May 9 due to hip pain. The world number 17's withdrawal raises questions about his readiness for the French Open later this month.
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Top French player Arthur Fils withdrew on Saturday against Andrea Pellegrino at the Rome Masters 1000 after feeling hip pain.
Katie Boulter suffered a first-round exit at Wimbledon, losing 6-4, 6-2 to Italian qualifier Tyra Grant in 66 minutes. The British player broke down during her post-match press conference while reflecting on the result.
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Jakub Mensik defeated Mariano Navone in a grueling five-set match at Roland Garros on Wednesday before collapsing on the court from cramps. The 20-year-old Czech player required medical attention but eventually walked off under his own power.