生物技术

Researchers in Israel have used CRISPR gene editing to deactivate a gene that produces bitter chemicals in grapefruit, potentially making the fruit more appealing to consumers. This innovation could expand the market for citrus and combat the devastating citrus greening disease by enabling cold-hardy, edible varieties. The approach aims to shift citrus farming to temperate regions like northern Europe.

January 29, 2026 由 AI 报道

Researchers have created a detailed brain organoid mimicking the developing cerebral cortex, complete with blood vessels that closely resemble those in a real brain. This advance addresses a key limitation in lab-grown mini-brains, potentially allowing them to survive longer and provide deeper insights into neurological conditions. The organoid, grown from human stem cells, features evenly distributed vessels with hollow centers, marking a significant step forward in brain research.

中国生物技术公司SciNeuro制药与瑞士制药巨头诺华周一宣布达成一项价值近17亿美元的合作协议，旨在开发治疗阿尔茨海默病的药物，该病影响全球约5500万人。 该协议授予诺华独家全球权利，开发和商业化SciNeuro的抗体候选物，以针对这种进行性脑部疾病。 SciNeuro的新型淀粉样蛋白β靶向抗体项目利用专有血脑屏障穿梭技术，帮助更多药物进入大脑发生阿尔茨海默病损伤的区域。

January 09, 2026 由 AI 报道

Researchers have produced the most detailed maps yet of how human DNA folds and reorganizes in three dimensions and over time. This work, led by scientists at Northwestern University as part of the 4D Nucleome Project, highlights how genome architecture influences gene activity and disease risk. The findings, published in Nature, could accelerate the discovery of genetic mutations linked to illnesses like cancer.