Biotechnology
Researchers in Israel have used CRISPR gene editing to deactivate a gene that produces bitter chemicals in grapefruit, potentially making the fruit more appealing to consumers. This innovation could expand the market for citrus and combat the devastating citrus greening disease by enabling cold-hardy, edible varieties. The approach aims to shift citrus farming to temperate regions like northern Europe.
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Researchers have created a detailed brain organoid mimicking the developing cerebral cortex, complete with blood vessels that closely resemble those in a real brain. This advance addresses a key limitation in lab-grown mini-brains, potentially allowing them to survive longer and provide deeper insights into neurological conditions. The organoid, grown from human stem cells, features evenly distributed vessels with hollow centers, marking a significant step forward in brain research.
Chinese biotech firm SciNeuro Pharmaceuticals has partnered with Swiss pharmaceutical giant Novartis in a deal worth nearly $1.7 billion to develop treatments for Alzheimer's disease, which affects some 55 million people worldwide. The agreement grants Novartis exclusive worldwide rights to develop and commercialise SciNeuro's antibody candidates for the progressive brain disease. SciNeuro's novel amyloid beta-targeted antibody programme leverages proprietary blood-brain barrier shuttle technology to help more of the drug cross into the brain where Alzheimer's damage occurs.
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Researchers have produced the most detailed maps yet of how human DNA folds and reorganizes in three dimensions and over time. This work, led by scientists at Northwestern University as part of the 4D Nucleome Project, highlights how genome architecture influences gene activity and disease risk. The findings, published in Nature, could accelerate the discovery of genetic mutations linked to illnesses like cancer.
Global funds back China's largest biotech firms
January 21, 2026 05:36Scientists create synthetic viruses to fight superbugs
January 20, 2026 14:49He Jiankui plans gene editing for Alzheimer’s after prison term
January 20, 2026 10:37Encouraging results with Jusvinza for chikungunya patients
January 19, 2026 20:08Barnacle glue inspires new treatment for inflammatory bowel disease
January 07, 2026 10:35Expert concerns temper promise of CAR T therapy for aging gut
January 07, 2026 06:59Chinese drug makers strike record US$136 billion out-licensing deals in 2025
December 29, 2025 06:43China vital to Insilico’s plan for biotech’s AI ‘Einstein’ in drug discovery
December 27, 2025 07:13Researchers decode rare cancer-fighting plant compound
December 27, 2025 06:29Researchers identify cancer cells' dependence on risky DNA repair mechanism