Longevity startup doses first patient in vision loss trial

A longevity startup has administered its first dose of a cellular rejuvenation therapy to a patient. The move follows recent FDA approval for human clinical trials of the treatment known as ER-100.

The therapy targets age-related sight loss as its initial focus. Company officials confirmed the dosing took place after regulators cleared the drug for trials. Vision restoration is the primary goal at this stage. The treatment may later address other conditions tied to aging. This marks an early step in efforts to apply cellular rejuvenation methods in people. The startup has not released details on the patient's condition or trial location.

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A widely studied anti-aging treatment triggered significant brain damage in mice, according to new research from the University of Connecticut. The drug combination dasatinib plus quercetin caused myelin loss and changes resembling those seen in multiple sclerosis. The findings raise questions about its use in longevity studies and off-label therapies.

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Researchers at Texas A&M University have developed a nasal spray that appears to reverse aspects of brain aging after just two doses. The treatment reduced inflammation and restored memory function in models for months afterward. The findings were published in the Journal of Extracellular Vesicles.

Tenaya Therapeutics, Inc. released a slide deck on May 17, 2026, covering results from its RIDGE-1 Phase Ib/II trial of TN-401 gene therapy. The presentation focuses on treatment for PKP2-associated arrhythmogenic right ventricular cardiomyopathy.

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Sequencio, a new Hong Kong unit of CK Life Sciences, is advancing about 20 cancer vaccine projects via China's faster pathway to human trials. CK Life Sciences vice-president and chief scientific officer Dr Melvin Toh Kean-meng said the firm plans investigator-initiated trials next year.

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