Gastroenterology

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Lancet review questions gluten as main driver of most ‘gluten sensitivity’ symptoms

Heather Vogel Fact checked

A University of Melbourne–led review published in The Lancet on October 22, 2025, argues that many symptoms attributed to non‑coeliac gluten sensitivity are more often linked to FODMAPs, other wheat components, and gut–brain interactions than to gluten itself. The authors call for better diagnostics, individualized care, and a shift away from unnecessary gluten avoidance.

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