Dementia

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Elderly woman describing a picture in a lab with speech pauses indicated, related to cognitive study
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Pauses and filler words in picture descriptions were linked to executive function in a Baycrest-led study

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Small speech timing habits—such as silent pauses, “um” and “uh,” and difficulty finding words—were associated with performance on standard executive-function tests in a study by researchers at Baycrest, the University of Toronto and York University.

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

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A study involving 73 people with mild cognitive impairment or early dementia found that tailored treatment plans targeting nutritional deficiencies, infections and other factors led to significant cognitive improvements after nine months. Participants in the intervention group saw their overall cognitive scores rise by 13.7 points, while the control group declined by 4.5 points. The approach combines medical interventions with lifestyle changes like diet, exercise and cognitive training.

A University of Exeter-led study funded by Alzheimer’s Society has identified three already-approved medicines—the shingles vaccine Zostavax, sildenafil (Viagra) and riluzole—as top “priority” candidates to be tested in clinical trials for Alzheimer’s disease, after a structured review of 80 existing drugs by an international expert panel.

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Lance Hammer's Queen at Sea, his first feature in 18 years since Ballast, premiered at the Berlin Film Festival. The film stars Juliette Binoche and Tom Courtenay in a story exploring consent and autonomy amid dementia. It presents a nuanced drama of family tensions and caregiving challenges.

A long-term analysis of more than 200,000 UK Biobank participants found that diets with lower glycemic index values were associated with a lower risk of dementia, including Alzheimer’s disease and vascular dementia, while higher dietary glycemic load was tied to a higher risk.

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A new study reveals that despite guidelines, about one in four Medicare beneficiaries with dementia continue to receive brain-altering medications linked to falls and confusion. Prescribing rates have declined overall from 20% to 16% between 2013 and 2021, but those with cognitive impairment face higher risks. Researchers highlight the need for better documentation and alternatives to improve care safety.

 

 

 

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