치매

A large study of nearly 2 million older adults has found that cerebral amyloid angiopathy, a condition where amyloid proteins build up in brain blood vessels, sharply increases the risk of dementia. Within five years of diagnosis, people with this disorder were four times more likely to develop dementia than those without it, even absent a history of stroke. The findings, drawn from Medicare records, underscore the need for early cognitive screening in affected individuals.

2026년 01월 29일 AI에 의해 보고됨

Scientists have created innovative nanoparticles designed to destroy harmful proteins linked to dementia and cancer. These particles can access difficult tissues like the brain and precisely eliminate problematic proteins without broad side effects. The technology shows early promise for precision medicine.

알츠하이머 시험이 암 연구에서 영감을 받은 다중 표적 접근으로 전환 중이며, Novo Nordisk의 세마글루타이드 실패에도 불구하고. Eli Lilly의 Kisunla와 Eisai 및 Biogen의 Leqembi 두 약물만이 진행을 늦추기 위해 널리 승인됨. 이러한 진화는 뇌 퇴화 질환을 복잡한 시스템으로 간주하며, 전 세계적 영향 속에서 이를 멈추는 새로운 방법을 모색함.

2025년 12월 09일 AI에 의해 보고됨 사실 확인됨

Researchers in Germany have identified a rare mutation in the GPX4 enzyme that disables its protective role in neurons, allowing toxic lipid peroxides to damage cell membranes and trigger ferroptotic cell death. Studies in patient-derived cells and mice show a pattern of neurodegeneration that resembles changes seen in Alzheimer’s disease and other dementias.

Washington University scientists report that inhibiting the circadian regulator REV-ERBα raised brain NAD+ and reduced tau pathology in mouse models, pointing to a clock-focused strategy worth exploring for Alzheimer’s disease.

2025년 10월 29일 AI에 의해 보고됨 사실 확인됨

A double‑blind McGill University–led clinical trial reports that 10 weeks of BrainHQ exercises increased a PET marker of cholinergic function in healthy older adults by an amount the authors say roughly offsets about a decade of age‑related decline. The peer‑reviewed study used a specialized tracer to confirm the biochemical change.