Dementia

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

24 Mwezi wa nne, 2026 Imeripotiwa na AI

A study involving 73 people with mild cognitive impairment or early dementia found that tailored treatment plans targeting nutritional deficiencies, infections and other factors led to significant cognitive improvements after nine months. Participants in the intervention group saw their overall cognitive scores rise by 13.7 points, while the control group declined by 4.5 points. The approach combines medical interventions with lifestyle changes like diet, exercise and cognitive training.

Lance Hammer's Queen at Sea, his first feature in 18 years since Ballast, premiered at the Berlin Film Festival. The film stars Juliette Binoche and Tom Courtenay in a story exploring consent and autonomy amid dementia. It presents a nuanced drama of family tensions and caregiving challenges.

11 Mwezi wa pili, 2026 Imeripotiwa na AI Imethibitishwa ukweli

Depression diagnosed for the first time in older adults was more common in the years leading up to a diagnosis of Parkinson’s disease or Lewy body dementia and remained elevated for years afterward, according to a large Danish registry study. The authors said the pattern—stronger than in several other chronic illnesses—supports the possibility that depression can be an early feature of these neurodegenerative conditions rather than only an emotional response to disability.

A new study reveals that despite guidelines, about one in four Medicare beneficiaries with dementia continue to receive brain-altering medications linked to falls and confusion. Prescribing rates have declined overall from 20% to 16% between 2013 and 2021, but those with cognitive impairment face higher risks. Researchers highlight the need for better documentation and alternatives to improve care safety.

4 Mwezi wa kwanza, 2026 Imeripotiwa na AI Imethibitishwa ukweli

Older adults with weaker or more irregular daily rest-activity rhythms were more likely to be diagnosed with dementia over about three years, according to a study published in *Neurology*. The research also linked later-afternoon activity peaks to higher dementia risk, though it did not establish that disrupted circadian rhythms cause dementia.