Medicine
Reptile urine crystals may inform future approaches to gout and kidney stones
Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया
Scientists reporting in the Journal of the American Chemical Society examined solid urine from more than 20 reptile species and found tiny uric‑acid spheres that package waste while conserving water. The study, highlighted by the American Chemical Society and ScienceDaily, also suggests uric acid helps convert toxic ammonia into a less harmful solid, a mechanism that could guide future strategies against gout and kidney stones.
Retinal implant restores reading vision for patients with dry AMD
A clinical trial has shown that an innovative retinal implant called PRIMA, paired with augmented-reality glasses, enables blind patients with dry age-related macular degeneration to read again. The study, published in The New England Journal of Medicine, involved 38 participants across five countries, with 84% regaining the ability to recognize letters, numbers, and words. This marks a significant advancement in artificial vision for a condition affecting millions worldwide.
Scientists uncover early brain damage before MS symptoms
Researchers at UC San Francisco have found that multiple sclerosis damages the brain years before symptoms appear, by analyzing blood proteins. The study identifies key markers like IL-3 and MOG, potentially enabling earlier diagnosis and prevention. This discovery, published in Nature Medicine, could transform how MS is managed.
Actor Satish Shah undergoes kidney transplant
Veteran Indian actor Satish Shah has undergone a kidney transplant following a history of dialysis and a heart procedure. Medical experts affirm that such transplants are safe when performed at reputable centers, boasting a success rate of around 98 percent. The procedure raises broader questions about kidney disease treatment in India.
British woman survives 38 years after heart-lung transplant
22 अक्टूबर 2025 20:00Wegovy provides heart benefits even with minimal weight loss
22 अक्टूबर 2025 18:01Vitamin D supplements slow telomere shortening in new study
22 अक्टूबर 2025 11:36WHO reports sharp rise in antibiotic resistance
22 अक्टूबर 2025 08:42New guidelines identify effective diets for chronic constipation
22 अक्टूबर 2025 03:10Stanford implant restores reading vision for macular degeneration patients
19 अक्टूबर 2025 00:14Study finds GLP-1 drugs may slow alcohol effects
19 अक्टूबर 2025 00:14Cleveland Clinic study shows surgery outperforms GLP-1 drugs for obesity and diabetes
Weight-loss drugs show early promise for alcohol and other addictions, review finds
Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया
Medications such as semaglutide (marketed as Ozempic/Wegovy) could aid treatment of alcohol and other substance use disorders, according to a peer‑reviewed review in the Journal of the Endocrine Society. Early animal and human data suggest these GLP‑1 receptor agonists act on brain reward circuits; lead author Lorenzo Leggio urged caution, saying, “Early research in both animals and humans suggests that these treatments may help reduce alcohol and other substance use.”
Low-dose radiation therapy eases knee osteoarthritis pain
A Korean clinical trial has demonstrated that low-dose radiation therapy significantly reduces pain and improves mobility in patients with mild to moderate knee osteoarthritis, outperforming placebo effects. The treatment, which uses doses far below those for cancer, showed no side effects and could serve as an alternative to medications or surgery. Results were presented at the American Society for Radiation Oncology Annual Meeting.
Fatty acid supplementation reverses age-related vision decline in mice
AI द्वारा रिपोर्ट किया गया
Researchers at UC Irvine have demonstrated that supplementing mice with a specific polyunsaturated fatty acid can restore visual function and reverse signs of cellular aging in the retina. The study targets the ELOVL2 gene, linked to age-related vision loss and macular degeneration. Published in Science Translational Medicine, the findings suggest potential therapies beyond DHA supplementation.
New DNA-based therapy reduces cholesterol by nearly 50 percent
Researchers from the University of Barcelona and the University of Oregon have developed a DNA-based treatment that targets the PCSK9 gene to lower cholesterol levels without the side effects of statins. Using polypurine hairpins, the therapy increases cholesterol uptake by cells and reduces artery-clogging lipids in animal models. The findings, published in Biochemical Pharmacology, suggest a safer alternative for preventing cardiovascular diseases.
CPD gene mutations tied to congenital hearing loss; lab tests point to arginine and sildenafil as potential interventions
Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया
An international team reports that rare mutations in CPD (carboxypeptidase D) cause a congenital, sensorineural form of hearing loss by disrupting arginine–nitric oxide signaling in inner‑ear hair cells. In models, arginine supplementation or sildenafil partially reversed disease‑related defects, highlighting a pathway for future therapies.
Study identifies aerobic exercise as top relief for knee osteoarthritis
A comprehensive review of over 200 studies has determined that aerobic exercises such as walking, cycling, and swimming provide the most effective pain relief and mobility improvements for people with knee osteoarthritis. Published in The BMJ, the analysis emphasizes aerobic activity as the foundation of treatment. All tested exercise types proved safe, with no increased adverse events compared to controls.
EMBL researchers unveil SDR-seq for decoding disease-linked DNA
Scientists at the European Molecular Biology Laboratory (EMBL) have developed SDR-seq, a new tool that simultaneously analyzes DNA and RNA in single cells. This innovation targets non-coding DNA regions, where over 95% of disease-associated genetic variants are located. The method promises to enhance understanding of complex diseases like heart disease, autism, and lymphoma.
Enhanced vitamin K analogues boost neuron regeneration
AI द्वारा रिपोर्ट किया गया
Researchers in Japan have developed synthetic vitamin K compounds that are three times more effective than natural versions at promoting neuron growth. These analogues, combined with retinoic acid, could offer new treatments for neurodegenerative diseases like Alzheimer's. The study highlights their ability to cross the blood-brain barrier and activate key brain receptors.