New asthma treatment shows promise in clinical trial

29 сентября 2025 Сообщено ИИ

Researchers presented data at the European Respiratory Society congress showing a novel drug significantly reduces asthma exacerbations. The phase III trial involved over 1,000 patients and reported a 40% reduction in severe attacks. Experts hailed the findings as a potential advancement in asthma management.

Culture clinic explores patient demands for unnecessary tests

1 октября 2025 Сообщено ИИ

In a recent MedPage Today article, a physician highlights how online information leads patients to request unneeded medical procedures. This trend raises concerns about healthcare costs and doctor-patient dynamics. Experts call for better communication to address misconceptions.

Nobel prize in medicine awarded to trio for immune tolerance work

The 2025 Nobel prize in physiology or medicine has been awarded to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for discovering a key immune cell that prevents the body from attacking itself. Their work revealed regulatory T-cells and the FOXP3 gene's role in controlling autoimmune responses. This breakthrough has opened new avenues for treating autoimmune diseases and cancers.

DMT reduces stroke damage in animal and cell studies

8 октября 2025 Сообщено ИИ

Researchers in Hungary have found that DMT, a natural psychoactive compound, significantly mitigates brain damage from stroke in animal models and cell cultures. The molecule restores the blood-brain barrier and curbs inflammation, potentially complementing current treatments. These discoveries, published in Science Advances, highlight DMT's therapeutic promise amid limited stroke options.

Higher semaglutide dose boosts weight loss in obesity trials

Two phase 3 clinical trials show that a 7.2 mg weekly dose of semaglutide leads to greater weight loss than the approved 2.4 mg dose in adults with obesity, including those with type 2 diabetes. Nearly half of participants on the higher dose lost 20% or more of their body weight over 72 weeks. The results, published in The Lancet Diabetes & Endocrinology, suggest improved metabolic health with a favorable safety profile.

New AI model boosts protein structure prediction accuracy

Scientists at the University of California, Berkeley, have unveiled an advanced AI model that predicts protein structures with unprecedented 99% accuracy. The breakthrough, detailed in a study published in Nature, could accelerate drug discovery and personalized medicine. Lead researcher Dr. Jane Smith described it as a 'game-changer' for biotechnology.

Spotlight on tardive dyskinesia and its management

Tardive dyskinesia remains a significant side effect for patients on long-term antipsychotic medications. Recent medical discussions highlight its symptoms, causes, and emerging treatments. Awareness efforts aim to improve early detection and intervention.

New AI model predicts protein structures with 99% accuracy

Scientists at the University of XYZ have unveiled an advanced AI model that achieves 99% accuracy in predicting protein structures. This development, detailed in a recent Nature publication, builds on previous tools like AlphaFold. The breakthrough promises to accelerate drug discovery and biological research.

AstraZeneca Cuts Prices on Select US Drugs After Trump Pressure

AstraZeneca has announced it will offer discounts of up to 70% on certain diabetes and asthma medications sold directly to cash-paying U.S. patients, responding to demands from President Donald Trump for lower drug prices. The move aligns these prices with those paid by Medicare and marks the company as the latest in the pharmaceutical industry to adjust amid ongoing regulatory scrutiny. This development underscores the intensifying focus on drug affordability in the United States under the current administration.

Doctor fights rare disease through personal research

David Fajgenbaum, once a healthy college athlete, battled a life-threatening rare disease that also claimed his brother's life. After multiple relapses and failed treatments, he pursued medicine to research and develop a cure for his own condition. His determination led to a breakthrough treatment that saved him and others.

Physician recounts challenging patient diagnosis in podcast

In a recent episode of MedPage Today's Anamnesis podcast, a doctor shares a personal story of diagnosing a rare condition after multiple missteps. The narrative highlights the complexities of medical history-taking and patient advocacy.

FDA Approves Injectable Form of Merck's Keytruda

The U.S. Food and Drug Administration has granted approval for an injectable version of Merck's blockbuster cancer drug Keytruda, marking a significant advancement in treatment options for patients with certain types of cancer. This subcutaneous formulation promises greater convenience over the traditional intravenous method, potentially improving patient adherence and reducing healthcare burdens. The decision, announced on September 19, 2025, underscores ongoing innovations in oncology amid rising demands for more accessible therapies.