Personalized Medicine
Gut methane may shape how many calories people absorb from fiber, ASU study finds
Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया
Arizona State University researchers report that people who produce more methane in the gut tend to extract more metabolizable energy from a fiber‑rich diet, pointing to microbiome differences that could inform personalized nutrition. The work appears in The ISME Journal (2025) and was highlighted by ASU on October 24, 2025.
Scientists create mini human livers to predict drug toxicities
Researchers at Cincinnati Children's Hospital Medical Center and Roche have developed a human liver organoid microarray platform that models immune-driven drug reactions. This system, built from patient-derived stem cells and immune cells, accurately replicates toxicities like those from flucloxacillin in genetically susceptible individuals. The findings were published online on September 26, 2025, in Advanced Science.
EMBL researchers unveil SDR-seq for decoding disease-linked DNA
Scientists at the European Molecular Biology Laboratory (EMBL) have developed SDR-seq, a new tool that simultaneously analyzes DNA and RNA in single cells. This innovation targets non-coding DNA regions, where over 95% of disease-associated genetic variants are located. The method promises to enhance understanding of complex diseases like heart disease, autism, and lymphoma.
Scientists reverse brain aging in mice using stem cells
Researchers at Cedars-Sinai have developed young immune cells from human stem cells that reversed signs of aging and Alzheimer's disease in mice. The treatment improved memory and brain structure in the animals. The findings, published in Advanced Science, suggest potential for personalized therapies against cognitive decline.
Lancet review questions gluten as main driver of most ‘gluten sensitivity’ symptoms
Heather Vogel तथ्य-जाँच किया गया
A University of Melbourne–led review published in The Lancet on October 22, 2025, argues that many symptoms attributed to non‑coeliac gluten sensitivity are more often linked to FODMAPs, other wheat components, and gut–brain interactions than to gluten itself. The authors call for better diagnostics, individualized care, and a shift away from unnecessary gluten avoidance.
Drug combination slows progression of aggressive prostate cancer
A phase III trial has shown that adding niraparib to standard prostate cancer therapy significantly delays disease progression in men with specific DNA repair gene mutations. The AMPLITUDE study, involving 696 men across 32 countries, reported a 37% reduced risk of cancer growth overall and 48% in BRCA-mutated cases. This marks a step toward precision medicine for advanced prostate cancer.