Study finds beta blockers offer no benefit after uncomplicated heart attacks

25 maggio 2026

Riportato dall'IA

A major international trial has found that beta blockers provide no benefit for patients who suffer uncomplicated heart attacks but retain normal heart function. The REBOOT trial results challenge decades of standard medical practice. Women in the study faced higher risks when taking the drugs.

The REBOOT trial enrolled 8505 patients across 109 hospitals in Spain and Italy. Participants were randomly assigned to receive beta blockers or avoid them after hospital discharge, while all received modern standard care. Researchers followed them for a median of nearly four years and found no significant reduction in death, repeat heart attacks, or heart failure hospitalizations among those with preserved heart function.

Finerenone slows kidney decline in non-diabetic CKD trial; pooled analysis suggests broader benefits across CKD

08 giugno 2026 Riportato dall'IA Immagine generata dall'IA Verificato

New data presented at the European Renal Association’s 63rd Congress in Glasgow and published in three major medical journals found that finerenone slowed kidney-function decline in adults with chronic kidney disease (CKD) without diabetes and reduced the risk of a combined kidney-and-cardiovascular outcome. A separate pooled analysis that combined results across finerenone studies also reported fewer kidney and heart-failure events in a broader CKD population.

Cochrane review questions benefits of anti-amyloid Alzheimer’s drugs

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

Review finds GLP-1 drugs linked to lower risk of heart attack, stroke and death in high-risk patients

21 maggio 2026 Riportato dall'IA Verificato

A large review of cardiovascular outcome trials found that people taking GLP-1 receptor agonists—drugs that include semaglutide (sold as Ozempic)—had a lower risk of major heart-related events than those given placebo. The analysis pooled results from 11 trials involving more than 90,000 participants, with an average follow-up of nearly three years, and reported benefits across patient subgroups including those with and without diabetes.

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A large U.S. study has found that 27 percent of patients with resistant hypertension have hypercortisolism, an excess of the stress hormone cortisol. The MOMENTUM study, involving 1,086 participants across 50 centers, showed this condition is far more common than previously thought in those whose blood pressure remains high despite multiple medications. The discovery suggests screening for elevated cortisol could help explain treatment failures.

Slow breathing calms anxiety without mindfulness in mice study

08 maggio 2026 Riportato dall'IA

A new study shows that slowing breathing rates can reduce anxiety-like behaviors even without any conscious effort or belief in its effects. Researchers used mice to demonstrate that the benefits come from physiological changes rather than placebo. The findings were presented at a summit in Los Angeles earlier this month.

28 maggio 2026 16:59

Study finds beta blockers offer no benefit after uncomplicated heart attacks

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