Estudo conclui que betabloqueadores não oferecem benefícios após infartos sem complicações

25 de maio de 2026

Reportado por IA

Um grande estudo internacional constatou que os betabloqueadores não trazem benefícios para pacientes que sofrem infartos sem complicações, mas mantêm a função cardíaca normal. Os resultados do estudo REBOOT desafiam décadas de prática médica padrão. As mulheres que participaram do estudo enfrentaram riscos maiores ao tomar os medicamentos.

O estudo REBOOT recrutou 8505 pacientes em 109 hospitais na Espanha e na Itália. Os participantes foram designados aleatoriamente para receber betabloqueadores ou evitá-los após a alta hospitalar, enquanto todos receberam cuidados padrão modernos. Os pesquisadores acompanharam os participantes por uma mediana de quase quatro anos e não encontraram redução significativa de mortes, novos infartos ou hospitalizações por insuficiência cardíaca entre aqueles com a função cardíaca preservada.

Finerenone slows kidney decline in non-diabetic CKD trial; pooled analysis suggests broader benefits across CKD

08 de junho de 2026 Reportado por IA Imagem gerada por IA Verificado

New data presented at the European Renal Association’s 63rd Congress in Glasgow and published in three major medical journals found that finerenone slowed kidney-function decline in adults with chronic kidney disease (CKD) without diabetes and reduced the risk of a combined kidney-and-cardiovascular outcome. A separate pooled analysis that combined results across finerenone studies also reported fewer kidney and heart-failure events in a broader CKD population.

Cochrane review questions benefits of anti-amyloid Alzheimer’s drugs

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

Review finds GLP-1 drugs linked to lower risk of heart attack, stroke and death in high-risk patients

21 de maio de 2026 Reportado por IA Verificado

A large review of cardiovascular outcome trials found that people taking GLP-1 receptor agonists—drugs that include semaglutide (sold as Ozempic)—had a lower risk of major heart-related events than those given placebo. The analysis pooled results from 11 trials involving more than 90,000 participants, with an average follow-up of nearly three years, and reported benefits across patient subgroups including those with and without diabetes.

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Study reveals excess cortisol in 27% of resistant hypertension patients

A large U.S. study has found that 27 percent of patients with resistant hypertension have hypercortisolism, an excess of the stress hormone cortisol. The MOMENTUM study, involving 1,086 participants across 50 centers, showed this condition is far more common than previously thought in those whose blood pressure remains high despite multiple medications. The discovery suggests screening for elevated cortisol could help explain treatment failures.

Slow breathing calms anxiety without mindfulness in mice study

08 de maio de 2026 Reportado por IA

A new study shows that slowing breathing rates can reduce anxiety-like behaviors even without any conscious effort or belief in its effects. Researchers used mice to demonstrate that the benefits come from physiological changes rather than placebo. The findings were presented at a summit in Los Angeles earlier this month.

quinta-feira, 28 de maio de 2026, 16:59h

Estudo conclui que betabloqueadores não oferecem benefícios após infartos sem complicações

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