دراسة تتوصل إلى أن حاصرات بيتا لا تقدم أي فائدة بعد النوبات القلبية غير المصحوبة بمضاعفات

25 مايو، 2026

من إعداد الذكاء الاصطناعي

توصلت تجربة دولية كبرى إلى أن حاصرات بيتا لا تقدم أي فائدة للمرضى الذين يعانون من نوبات قلبية غير مصحوبة بمضاعفات ويحتفظون بوظائف قلب طبيعية. وتتحدى نتائج تجربة REBOOT عقوداً من الممارسات الطبية القياسية. وقد واجهت النساء المشاركات في الدراسة مخاطر أعلى عند تناول هذه الأدوية.

شملت تجربة REBOOT 8505 مريضاً في 109 مستشفيات في إسبانيا وإيطاليا. تم تقسيم المشاركين عشوائياً لتلقي حاصرات بيتا أو تجنبها بعد الخروج من المستشفى، في حين تلقى الجميع الرعاية القياسية الحديثة. تابع الباحثون حالة المشاركين لمدة متوسطها قرابة أربع سنوات، ولم يجدوا أي انخفاض ملموس في حالات الوفاة، أو تكرار النوبات القلبية، أو دخول المستشفى بسبب فشل القلب بين أولئك الذين يتمتعون بوظائف قلب طبيعية.

Finerenone slows kidney decline in non-diabetic CKD trial; pooled analysis suggests broader benefits across CKD

8 يونيو، 2026 من إعداد الذكاء الاصطناعي صورة مولدة بواسطة الذكاء الاصطناعي تم التحقق من الحقائق

New data presented at the European Renal Association’s 63rd Congress in Glasgow and published in three major medical journals found that finerenone slowed kidney-function decline in adults with chronic kidney disease (CKD) without diabetes and reduced the risk of a combined kidney-and-cardiovascular outcome. A separate pooled analysis that combined results across finerenone studies also reported fewer kidney and heart-failure events in a broader CKD population.

Cochrane review questions benefits of anti-amyloid Alzheimer’s drugs

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

Review finds GLP-1 drugs linked to lower risk of heart attack, stroke and death in high-risk patients

21 مايو، 2026 من إعداد الذكاء الاصطناعي تم التحقق من الحقائق

A large review of cardiovascular outcome trials found that people taking GLP-1 receptor agonists—drugs that include semaglutide (sold as Ozempic)—had a lower risk of major heart-related events than those given placebo. The analysis pooled results from 11 trials involving more than 90,000 participants, with an average follow-up of nearly three years, and reported benefits across patient subgroups including those with and without diabetes.

صحة

Single-dose zilebesiran as add-on therapy lowers systolic blood pressure in KARDIA-2 trial

صحة

Brief bursts of vigorous activity tied to lower risks across eight major disease groups, study finds

صحة

Vanderbilt study finds muscle loss with weight loss drugs and surgery

Study reveals excess cortisol in 27% of resistant hypertension patients

A large U.S. study has found that 27 percent of patients with resistant hypertension have hypercortisolism, an excess of the stress hormone cortisol. The MOMENTUM study, involving 1,086 participants across 50 centers, showed this condition is far more common than previously thought in those whose blood pressure remains high despite multiple medications. The discovery suggests screening for elevated cortisol could help explain treatment failures.

Slow breathing calms anxiety without mindfulness in mice study

8 مايو، 2026 من إعداد الذكاء الاصطناعي

A new study shows that slowing breathing rates can reduce anxiety-like behaviors even without any conscious effort or belief in its effects. Researchers used mice to demonstrate that the benefits come from physiological changes rather than placebo. The findings were presented at a summit in Los Angeles earlier this month.

28 مايو 2026 16:59

دراسة تتوصل إلى أن حاصرات بيتا لا تقدم أي فائدة بعد النوبات القلبية غير المصحوبة بمضاعفات

مقالات ذات صلة

Finerenone slows kidney decline in non-diabetic CKD trial; pooled analysis suggests broader benefits across CKD

Cochrane review questions benefits of anti-amyloid Alzheimer’s drugs

Review finds GLP-1 drugs linked to lower risk of heart attack, stroke and death in high-risk patients

Single-dose zilebesiran as add-on therapy lowers systolic blood pressure in KARDIA-2 trial

Brief bursts of vigorous activity tied to lower risks across eight major disease groups, study finds

Vanderbilt study finds muscle loss with weight loss drugs and surgery

Study reveals excess cortisol in 27% of resistant hypertension patients

Slow breathing calms anxiety without mindfulness in mice study

Small JAMA Psychiatry trial suggests immune-targeting drug may help some treatment-resistant depression symptoms

Gene-editing drug slashes bad cholesterol 62 percent in trial

Irregular bedtimes in midlife linked to higher heart risks

Study links common IBS drugs to higher long-term death risk

Hitting urate targets with gout-lowering therapy is linked to lower cardiovascular risk in large UK study

Evolocumab reduces heart attack risk by 31% in high-risk diabetes patients

Stroke prompts rejuvenation-like changes in undamaged brain areas

Shingles vaccine cuts heart risks nearly in half in study

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