Studi menemukan penghambat beta tidak memberikan manfaat setelah serangan jantung tanpa komplikasi

Senin, 25 Mei 2026

Dilaporkan oleh AI

Sebuah uji klinis internasional berskala besar menemukan bahwa penghambat beta (beta blockers) tidak memberikan manfaat bagi pasien yang mengalami serangan jantung tanpa komplikasi namun tetap memiliki fungsi jantung normal. Hasil uji coba REBOOT ini menantang standar praktik medis yang telah berlangsung selama beberapa dekade. Wanita dalam penelitian tersebut menghadapi risiko lebih tinggi saat mengonsumsi obat-obatan ini.

Uji coba REBOOT melibatkan 8.505 pasien di 109 rumah sakit di Spanyol dan Italia. Peserta secara acak ditugaskan untuk menerima penghambat beta atau tidak mengonsumsinya setelah keluar dari rumah sakit, sementara semuanya menerima standar perawatan modern. Para peneliti memantau mereka selama rata-rata hampir empat tahun dan menemukan tidak adanya penurunan signifikan dalam kematian, serangan jantung berulang, atau rawat inap akibat gagal jantung di antara mereka yang memiliki fungsi jantung terjaga.

Finerenone slows kidney decline in non-diabetic CKD trial; pooled analysis suggests broader benefits across CKD

Senin, 08 Juni 2026 Dilaporkan oleh AI Gambar dihasilkan oleh AI Fakta terverifikasi

New data presented at the European Renal Association’s 63rd Congress in Glasgow and published in three major medical journals found that finerenone slowed kidney-function decline in adults with chronic kidney disease (CKD) without diabetes and reduced the risk of a combined kidney-and-cardiovascular outcome. A separate pooled analysis that combined results across finerenone studies also reported fewer kidney and heart-failure events in a broader CKD population.

Cochrane review questions benefits of anti-amyloid Alzheimer’s drugs

A major Cochrane review of 17 clinical trials involving over 20,000 participants has concluded that drugs targeting amyloid beta in the brain provide no meaningful benefits for patients with mild cognitive impairment or early Alzheimer’s. These treatments also raise the risk of brain swelling and bleeding. Researchers urge a shift to alternative pathways for future treatments.

Review finds GLP-1 drugs linked to lower risk of heart attack, stroke and death in high-risk patients

Kamis, 21 Mei 2026 Dilaporkan oleh AI Fakta terverifikasi

A large review of cardiovascular outcome trials found that people taking GLP-1 receptor agonists—drugs that include semaglutide (sold as Ozempic)—had a lower risk of major heart-related events than those given placebo. The analysis pooled results from 11 trials involving more than 90,000 participants, with an average follow-up of nearly three years, and reported benefits across patient subgroups including those with and without diabetes.

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Brief bursts of vigorous activity tied to lower risks across eight major disease groups, study finds

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Vanderbilt study finds muscle loss with weight loss drugs and surgery

Study reveals excess cortisol in 27% of resistant hypertension patients

A large U.S. study has found that 27 percent of patients with resistant hypertension have hypercortisolism, an excess of the stress hormone cortisol. The MOMENTUM study, involving 1,086 participants across 50 centers, showed this condition is far more common than previously thought in those whose blood pressure remains high despite multiple medications. The discovery suggests screening for elevated cortisol could help explain treatment failures.

Slow breathing calms anxiety without mindfulness in mice study

Jumat, 08 Mei 2026 Dilaporkan oleh AI

A new study shows that slowing breathing rates can reduce anxiety-like behaviors even without any conscious effort or belief in its effects. Researchers used mice to demonstrate that the benefits come from physiological changes rather than placebo. The findings were presented at a summit in Los Angeles earlier this month.

28 Mei 2026 16.59

Studi menemukan penghambat beta tidak memberikan manfaat setelah serangan jantung tanpa komplikasi

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