Illustration of a doctor discussing positive kidney treatment results with a patient using digital graphs.
Illustration of a doctor discussing positive kidney treatment results with a patient using digital graphs.
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Finerenone perlambat penurunan fungsi ginjal pada uji klinis CKD non-diabetes; analisis gabungan tunjukkan manfaat lebih luas bagi penderita CKD

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Fakta terverifikasi

Data baru yang dipresentasikan pada Kongres ke-63 European Renal Association di Glasgow dan diterbitkan dalam tiga jurnal medis utama menemukan bahwa finerenone memperlambat penurunan fungsi ginjal pada orang dewasa dengan penyakit ginjal kronis (CKD) tanpa diabetes serta mengurangi risiko hasil gabungan terkait ginjal dan kardiovaskular. Sebuah analisis gabungan terpisah yang mengintegrasikan hasil dari berbagai studi finerenone juga melaporkan penurunan kejadian gagal ginjal dan gagal jantung pada populasi CKD yang lebih luas.

Para peneliti melaporkan hasil tersebut pada Kongres ke-63 European Renal Association (ERA) di Glasgow, Skotlandia, dengan publikasi simultan yang terkait dengan presentasi tersebut di The New England Journal of Medicine, JAMA, dan The Lancet.

Apa yang dikatakan orang

Reaksi awal di X menyoroti temuan positif dari uji klinis FIND-CKD yang menunjukkan bahwa finerenone memperlambat penurunan eGFR pada pasien CKD non-diabetes, dengan pengurangan risiko sebesar 23% pada kejadian ginjal dan kardiovaskular, serta manfaat serupa dalam analisis gabungan pada populasi CKD yang lebih luas. Para profesional medis dan jurnal mengekspresikan antusiasme terhadap perluasan indikasi di luar diabetes.

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