Stem Cells

Illustration of USC researchers preparing dopamine-producing stem cell implants for early-stage Parkinson’s trial.

USC researchers begin early trial of dopamine-producing stem cell implants for Parkinson’s

06 febbraio 2026 Riportato dall'IA Immagine generata dall'IA Verificato

Keck Medicine of USC researchers are testing an experimental approach to Parkinson’s disease that implants lab-grown, dopamine-producing cells into a movement-control region of the brain. The early-stage Phase 1 REPLACE trial involves up to 12 people with moderate to moderate-severe Parkinson’s disease, and the U.S. Food and Drug Administration has granted the study fast-track designation.

Swedish team restores blood sugar control in diabetic mice

Researchers in Sweden have created insulin-producing cells from human stem cells that reversed diabetes symptoms when transplanted into mice. The cells matured after placement in the eye and maintained glucose regulation for months. The work was published in Stem Cell Reports.

Stem cell therapy eases frailty in older adults

27 febbraio 2026 Riportato dall'IA

An experimental therapy using stem cells from young donors has shown promise in improving mobility for frail older people. In a trial involving 148 participants, infusions of laromestrocel led to significant gains in walking distance. Researchers highlight its potential to address biological roots of frailty.

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Nanoflowers supercharge stem cells to recharge aging tissues

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Stanford dual-transplant therapy prevents and reverses type 1 diabetes in mice

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Stem cell therapy restores vision in AMD patients

Fat-derived stem cells repair osteoporotic-type spine fractures in rats

Researchers at Osaka Metropolitan University report that stem cells taken from body fat, formed into bone-leaning spheroids and paired with a common bone-reconstruction material, improved healing and strength in rat models of osteoporotic vertebral fractures. The preclinical findings, published in Bone & Joint Research, point to a potential future therapy if validated in humans.

Stanford antibody regimen enables stem cell transplants without radiation or busulfan in Fanconi anemia

08 novembre 2025 Riportato dall'IA Verificato

A Stanford Medicine team reports that a single dose of the anti‑CD117 antibody briquilimab allowed three children with Fanconi anemia to undergo stem cell transplants without radiation or busulfan, achieving near‑complete donor cell engraftment in a phase 1b study published in Nature Medicine.

Scientists reverse brain aging in mice using stem cells

Researchers at Cedars-Sinai have developed young immune cells from human stem cells that reversed signs of aging and Alzheimer's disease in mice. The treatment improved memory and brain structure in the animals. The findings, published in Advanced Science, suggest potential for personalized therapies against cognitive decline.

MIT study finds cysteine boosts gut repair in mice

23 ottobre 2025 Riportato dall'IA

Researchers at MIT have discovered that the amino acid cysteine can enhance the small intestine's ability to heal itself. In experiments with mice, a cysteine-rich diet activated immune cells to promote tissue regeneration after damage from radiation or chemotherapy. The findings, published in Nature, suggest potential dietary strategies to mitigate treatment side effects.

20 febbraio 2026 10:05