Stem Cells
Study links graying hair and melanoma to stress responses in pigment stem cells
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Japanese researchers report that hair graying and melanoma can arise from the same melanocyte stem cells, which take different paths depending on DNA damage and local signals. Published online October 6, 2025 in Nature Cell Biology, the University of Tokyo-led study outlines a protective differentiation program that promotes graying and how carcinogens can subvert it to favor melanoma.
Scientists create mini human livers to predict drug toxicities
Researchers at Cincinnati Children's Hospital Medical Center and Roche have developed a human liver organoid microarray platform that models immune-driven drug reactions. This system, built from patient-derived stem cells and immune cells, accurately replicates toxicities like those from flucloxacillin in genetically susceptible individuals. The findings were published online on September 26, 2025, in Advanced Science.
Scientists create viable human eggs from skin cells
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Researchers at Oregon Health and Science University have successfully generated functional human egg cells from skin cells, which were then fertilized in the lab to produce early-stage embryos. This breakthrough, published in Nature, represents the first time such eggs have been matured and used for fertilization outside the body. The technique could eventually aid infertility treatments and genetic disease prevention.
Stem cell therapy lowers heart failure risk after heart attack
2025년 10월 23일 11시 03분Scientists reverse brain aging in mice using stem cells
2025년 10월 19일 00시 14분Stanford scientists scale up mini-brain production using xanthan gum
Electrical stimulation reprograms human immune cells to spur repair
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Trinity College Dublin researchers report that electrically stimulating human macrophages shifted them toward an anti‑inflammatory, tissue‑repairing state in laboratory tests, pointing to potential therapies for injuries and inflammatory disease. The peer‑reviewed findings appear in Cell Reports Physical Science.
Stem Cell EVs Aid Tissue Repair
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StemDAO is developing therapies using extracellular vesicles from stem cells to address soft tissue injuries, cognitive decline, and aging. Clinical data shows benefits in cognition, skin health, and inflammation reduction. This approach triggers natural regeneration without surgery.
Flatworm stem cells respond to distant cues, study finds
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Planarian flatworms regenerate lost body parts using stem cells steered by signals from far‑off tissues rather than nearby neighbors, research published in Cell Reports on October 15, 2025, suggests—reframing how niches regulate stem cells and hinting at future approaches to tissue repair.
MIT study finds cysteine boosts gut repair in mice
Researchers at MIT have discovered that the amino acid cysteine can enhance the small intestine's ability to heal itself. In experiments with mice, a cysteine-rich diet activated immune cells to promote tissue regeneration after damage from radiation or chemotherapy. The findings, published in Nature, suggest potential dietary strategies to mitigate treatment side effects.