Stem Cells
USC researchers begin early trial of dopamine-producing stem cell implants for Parkinson’s
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Keck Medicine of USC researchers are testing an experimental approach to Parkinson’s disease that implants lab-grown, dopamine-producing cells into a movement-control region of the brain. The early-stage Phase 1 REPLACE trial involves up to 12 people with moderate to moderate-severe Parkinson’s disease, and the U.S. Food and Drug Administration has granted the study fast-track designation.
Researchers at the University of Cambridge have developed miniature lab-grown models of the human brain and spinal cord that show damaged nerve fibers can regain the ability to regrow under certain conditions.
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Researchers in Sweden have created insulin-producing cells from human stem cells that reversed diabetes symptoms when transplanted into mice. The cells matured after placement in the eye and maintained glucose regulation for months. The work was published in Stem Cell Reports.
A pioneering clinical trial at the University of Michigan has demonstrated that adult stem cell transplants can safely improve vision in patients with advanced dry age-related macular degeneration. Early results from six participants show significant sight gains without serious side effects. Researchers are now evaluating higher doses in additional patients.
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Researchers at Osaka Metropolitan University report that stem cells taken from body fat, formed into bone-leaning spheroids and paired with a common bone-reconstruction material, improved healing and strength in rat models of osteoporotic vertebral fractures. The preclinical findings, published in Bone & Joint Research, point to a potential future therapy if validated in humans.
Japanese researchers report that hair graying and melanoma can arise from the same melanocyte stem cells, which take different paths depending on DNA damage and local signals. Published online October 6, 2025 in Nature Cell Biology, the University of Tokyo-led study outlines a protective differentiation program that promotes graying and how carcinogens can subvert it to favor melanoma.
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Researchers at Cedars-Sinai have developed young immune cells from human stem cells that reversed signs of aging and Alzheimer's disease in mice. The treatment improved memory and brain structure in the animals. The findings, published in Advanced Science, suggest potential for personalized therapies against cognitive decline.
Stem cell therapy eases frailty in older adults
Ijumaa, 20. Mwezi wa pili 2026, 10:05:28USC-led trial tests dopamine-producing stem cell implants for Parkinson’s
Jumanne, 20. Mwezi wa kwanza 2026, 03:55:31UBC researchers show how to reliably generate helper T cells from stem cells by tuning Notch signaling
Ijumaa, 9. Mwezi wa kwanza 2026, 04:42:21USC launches trial for tiny stem cell eye implant
Jumatano, 7. Mwezi wa kwanza 2026, 17:44:10Japanese scientists recreate human brain circuits in lab
Jumamosi, 8. Mwezi wa kumi na moja 2025, 10:57:26Stanford antibody regimen enables stem cell transplants without radiation or busulfan in Fanconi anemia
Ijumaa, 7. Mwezi wa kumi na moja 2025, 16:23:31Low serine levels push hair follicle stem cells to repair skin, study finds
Alhamisi, 30. Mwezi wa kumi 2025, 08:22:17Electrical stimulation reprograms human immune cells to spur repair
Alhamisi, 30. Mwezi wa kumi 2025, 01:00:08Flatworm stem cells respond to distant cues, study finds
Jumatano, 29. Mwezi wa kumi 2025, 15:18:30Stem cell therapy lowers heart failure risk after heart attack