Vaccini

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Photorealistic lab scene depicting DoriVac DNA origami vaccine triggering strong immune responses in mouse and organ chip models, as an advance over mRNA vaccines.
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DNA origami “DoriVac” shows strong immune activation in early tests, offering a potential complement to mRNA vaccines

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Researchers at Harvard’s Wyss Institute and Dana-Farber Cancer Institute report that a DNA origami-based vaccine platform called DoriVac generated robust immune responses in mice and in a human lymph node “Organ Chip” model. The team says the approach could be easier to store and manufacture than lipid nanoparticle–delivered mRNA vaccines, though the work remains preclinical. The results were published in Nature Biomedical Engineering.

A new study found that the shingles vaccine reduced major cardiac events by 46% and deaths by 66% in people with atherosclerotic heart disease. The research, presented at the American College of Cardiology's Annual Scientific Session, examined over 246,000 US adults aged 50 and older.

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Dr. Vinay Prasad, who leads the FDA division that oversees vaccines and other biological products, will leave the agency at the end of April, FDA Commissioner Marty Makary told staff in an email. It will be Prasad’s second departure in less than a year after a brief exit last summer amid clashes over high-profile drug and vaccine reviews.

The measles vaccine has averted 60 million deaths worldwide since 2000, yet low vaccination rates fueled by misinformation are causing outbreaks in several countries. A fraudulent 1998 study linking the MMR vaccine to autism continues to undermine public health efforts. Experts urge stronger measures to counter anti-vaccine disinformation on social media and beyond.

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Measles infections in the United States hit their highest level in over three decades last year, with 2,242 confirmed cases. A surging outbreak in South Carolina, which has infected more than 600 people since October, threatens to surpass a major incident in West Texas. This development signals another challenging year for public health ahead.

Nature Medicine ha selezionato studi clinici promettenti per il 2026, enfatizzando vaccini a lunga durata e trattamenti innovativi. Le aree chiave includono tubercolosi, HIV, long Covid, cellule staminali e colesterolo. Questi sviluppi potrebbero trasformare la lotta contro le malattie globali.

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L'Egitto ha raggiunto una tappa storica nello sviluppo biofarmaceutico con la posa della prima pietra per l'impianto vaccini Gennvax, destinato a essere il più grande complesso produttivo integrato in Medio Oriente e Africa. Il progetto promuove la localizzazione dei vaccini e la sicurezza nazionale dei farmaci. La cerimonia ha visto la presenza di alti funzionari e leader sanitari.

 

 

 

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