Impfstoffe
DNA origami “DoriVac” shows strong immune activation in early tests, offering a potential complement to mRNA vaccines
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Researchers at Harvard’s Wyss Institute and Dana-Farber Cancer Institute report that a DNA origami-based vaccine platform called DoriVac generated robust immune responses in mice and in a human lymph node “Organ Chip” model. The team says the approach could be easier to store and manufacture than lipid nanoparticle–delivered mRNA vaccines, though the work remains preclinical. The results were published in Nature Biomedical Engineering.
A new study found that the shingles vaccine reduced major cardiac events by 46% and deaths by 66% in people with atherosclerotic heart disease. The research, presented at the American College of Cardiology's Annual Scientific Session, examined over 246,000 US adults aged 50 and older.
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Dr. Vinay Prasad, who leads the FDA division that oversees vaccines and other biological products, will leave the agency at the end of April, FDA Commissioner Marty Makary told staff in an email. It will be Prasad’s second departure in less than a year after a brief exit last summer amid clashes over high-profile drug and vaccine reviews.
The measles vaccine has averted 60 million deaths worldwide since 2000, yet low vaccination rates fueled by misinformation are causing outbreaks in several countries. A fraudulent 1998 study linking the MMR vaccine to autism continues to undermine public health efforts. Experts urge stronger measures to counter anti-vaccine disinformation on social media and beyond.
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Measles infections in the United States hit their highest level in over three decades last year, with 2,242 confirmed cases. A surging outbreak in South Carolina, which has infected more than 600 people since October, threatens to surpass a major incident in West Texas. This development signals another challenging year for public health ahead.
Nature Medicine hat vielversprechende klinische Studien für 2026 ausgewählt, die langlebige Impfstoffe und innovative Behandlungen hervorheben. Wichtige Bereiche umfassen Tuberkulose, HIV, Long Covid, Stammzellen und Cholesterin. Diese Entwicklungen könnten den Kampf gegen globale Krankheiten verändern.
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Ägypten hat einen Meilenstein in der Biopharmazeutischen Entwicklung gesetzt mit der Grundsteinlegung für die Gennvax-Impfstoffanlage, die das größte integrierte Produktionskomplex im Nahen Osten und Afrika werden soll. Das Projekt fördert die Lokalisierung von Impfstoffen und die nationale Arzneimittelsicherheit. Die Zeremonie zog hochrangige Beamte und Gesundheitsführer an.
Shingles vaccine associated with slower biological aging
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Sonntag, 28. Dezember 2025, 07:44 UhrTrump orders HHS and CDC to review U.S. childhood vaccine recommendations and compare them with other countries