H3N2 K subclade flu spreads in South America, Argentina heightens surveillance

Following initial alerts in Europe and the US, the H3N2 influenza 'subclade K' variant is now advancing in Chile, Peru, and Colombia, prompting Argentina to analyze local samples amid concerns of higher infection and hospitalization risks.

The H3N2 K subclade, previously driving hospitalizations in Europe and the US, has been confirmed circulating in neighboring South American countries including Chile, Peru, and Colombia. This development has placed Argentine health authorities on high alert, as the variant is associated with elevated infection and hospitalization rates compared to prior strains.

The National Institute of Infectious Diseases Malbrán is actively testing local influenza samples to detect any presence in Argentina, a critical step for gauging national impact.

With symptoms akin to seasonal flu but potentially more severe in vulnerable populations, health officials reiterate standard precautions: vaccination, masks in crowded areas, hand hygiene, and isolation from symptomatic individuals. Prompt medical consultation is urged for flu-like illnesses.

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Realistic illustration of Indonesian doctors treating super flu patients in a Bandung hospital, with Java map highlighting affected areas, conveying controlled outbreak.
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Super flu cases detected in Central and West Java

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Central Java's Health Department detected one case of super flu, or influenza A H3N2 subclade K, in Semarang at the end of December 2025. Meanwhile, Hasan Sadikin Hospital in Bandung confirmed 10 cases in West Java from August to November 2025, with one patient dying due to comorbidities. Health officials stress that this is not a new virus and the situation is under control.

Following initial detections in neighboring South American countries, the H3N2 influenza A K subclade has now reached Argentina, with confirmed cases in Buenos Aires, Santa Cruz, and Neuquén, including hospitalizations for pneumonia. Authorities are advancing the 2026 flu vaccination campaign for at-risk groups, while current vaccines offer partial protection against severe illness, bolstered by antivirals like oseltamivir.

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A mutation of the influenza A virus, known as the H3N2 K subclade, has led to increased hospitalizations in Europe and the United States, though no more severe cases are reported. In Latin America, including Mexico, preventive surveillance is in place without this variant predominating. Authorities recommend vaccination for vulnerable groups amid the risk of spread.

Chile's National Service for Disaster Prevention and Response (Senapred) has declared a preventive early alert in the Araucanía Region after detecting highly pathogenic H5N1 avian influenza in backyard birds in Reinaco commune. The measure addresses a zoosanitary risk reported by the Agricultural and Livestock Service (SAG), amid a national emergency. The virus has now reached five regions.

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Chile's Agricultural and Livestock Service (SAG) detected a highly pathogenic H5N1 avian influenza case in backyard birds in Bollenar sector, Melipilla commune, Metropolitan Region. The virus was lab-confirmed after reports of domestic bird deaths. The country retains its sanitary status free of the disease in commercial flocks.

ブラジルとペルーの科学者は、気候変動により増加するデング熱を抑制するため、機械学習を用いた早期の感染予測や、ボルバキア菌に感染させた蚊の活用に取り組んでいる。2024年にリマで発生した流行は病院を逼迫させ、その教訓は現在、地域の対策に活かされている。これらの取り組みは、亜熱帯地域の米国内で発生している地域内感染のモデルケースとしても注目されている。

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Argentina's National Meteorological Service issued yellow alerts for Wednesday, November 26, in several southern provinces. The warnings cover storms in Chubut, Río Negro, and Neuquén, and rains in Tierra del Fuego and Santa Cruz. Residents are urged to monitor updates.

 

 

 

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